Glyoxylic Acid → HCID 11259991、化合物

HRID 891832

反応式

HRID 891832 の反応式
[C:1]([OH:5])(=[O:4])[CH:2]=O.[CH2:6]([S:12][S:13][CH2:14][C@H:15]([NH2:19])[C:16]([OH:18])=[O:17])[C@H:7]([NH2:11])[C:8]([OH:10])=[O:9].B([O-])([O-])[O-]>>[C:1]([CH2:2][N:11]([CH2:2][C:1]([OH:5])=[O:4])[C@H:7]([C:8]([OH:10])=[O:9])[CH2:6][S:12][S:13][CH2:14][C@H:15]([N:19]([CH2:15][C:16]([OH:18])=[O:17])[CH2:7][C:8]([OH:10])=[O:9])[C:16]([OH:18])=[O:17])([OH:5])=[O:4]

参加物

4

反応物 3

HCID 760Glyoxylic AcidHCID 26574BorateHCID 67678(-)-Cystine

生成物 1

HCID 11259991HCID 11259991、化合物

実験手順

The alternative route, relying on in solution phase synthesis of an intermediate product starts with addition of a large excess (40 times) of glyoxylic acid to L-cystine in an alkaline borate buffer. The intermediate product was thereafter, after pH manipulations and conductivity adjustment of the reaction mixture, purified with ion exchange chromatography to give N,N,N′,N′-tetrakis (carboxymethyl)-L-cystine.

後処理

  1. customThe alternative route, relying on in solution phase synthesis of an intermediate product
  2. customafter pH manipulations and conductivity adjustment of the reaction mixture, purified with ion exchange chromatography

出典と根拠

ORDレコード
ord-ce089f0ba7b44eafb0e7bc10f2374c60
出典データセット
uspto-grants-2006_02
特許番号
US07005071B2

関連ノート

読み込み中…