Acetyl chloride → 1-(2-Methyl-benzylidene)-piperidinium chloride

HRID 9009

反応式

HRID 9009 の反応式
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=O.C([Cl:19])(=O)C>>[Cl-:19].[CH3:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=[N+:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

4

反応物 3

HCID 6367Acetyl chlorideHCID 8082PiperidineHCID 107222-Methylbenzaldehyde

生成物 1

HCID 179122571-(2-Methyl-benzylidene)-piperidinium chloride

実験手順

The reaction of 9.5 ml (0.096 mol) piperidine and 4.7 ml (0.040 mol) 2-methylbenzaldehyde in accordance with general synthesis instructions 2 and subsequent reaction with 2.4 ml (0.040 mol) acetyl chloride in accordance with general synthesis instructions 3 gave 5.8 g (corresponding to 65% of the yield calculated by theory) 1-(2-methyl-benzylidene)-piperidinium chloride.

後処理

  1. customwith general synthesis instructions 3

出典と根拠

ORDレコード
ord-00adf1ba992d4cb99f816842b438f344
出典データセット
uspto-grants-2006_08
特許番号
US07091220B2

関連ノート

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