Chloroform → HCID 54162718、化合物

HRID 903114ノート

反応式

HRID 903114 の反応式
[Na].[CH:2]([CH:4]([CH2:7][NH:8][CH:9]=[O:10])[C:5]#[N:6])=O.[Cl-].[CH3:12][NH2+:13][CH3:14].C(Cl)(Cl)Cl>O>[CH3:12][N:13]([CH:2]=[C:4]([CH2:7][NH:8][CH:9]=[O:10])[C:5]#[N:6])[CH3:14]

参加物

6

反応物 4

HCID 6212ChloroformHCID 5360545SodiumHCID 12954980Dimethylazanium;chlorideHCID 21541183HCID 21541183、化合物

生成物 1

HCID 54162718HCID 54162718、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

98.6 parts of 75 percent pure sodium salt of α-formyl-β-formylaminopropionitrile and 81.5 parts of dimethylammonium chloride in 700 parts by volume of chloroform are refluxed for 1.5 hours, during which time 8.5 parts (theory: 9 parts) of water are eliminated. The mixture is filtered, the filtrate is concentrated to dryness and the product is recrystallized from methanol. 43.0 parts of α-dimethylaminomethylene-β-formylaminopropionitrile of melting point 90° C. are obtained.

後処理

  1. filtrationThe mixture is filtered
  2. concentrationthe filtrate is concentrated to dryness
  3. customthe product is recrystallized from methanol

出典と根拠

ORDレコード
ord-7d52ea1f9309424cbc163c5db1abd9c3
出典データセット
uspto-grants-1980_10
特許番号
US04226799

反応ノート

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