Hydrogen Bromide → 5-((2-Aminoethyl)thiomethyl)thiazole dihydrobromide
反応式
O[CH2:2][C:3]1[S:7][CH:6]=[N:5][CH:4]=1.Cl.[NH2:9][CH2:10][CH2:11][SH:12].CO.[BrH:15]>>[BrH:15].[BrH:15].[NH2:9][CH2:10][CH2:11][S:12][CH2:2][C:3]1[S:7][CH:6]=[N:5][CH:4]=1参加物
5
実験手順
The reaction of 5-hydroxymethylthiazole (2.01 g.) with cysteamine hydrochloride (1.99 g.) in aqueous hydrobromic acid by the method described in Example 1(i)(a) gave 5-[(2-aminoethyl)thiomethyl]thiazole dihydrobromide (4.85 g.), m.p. 191°-194° (from methanol).
出典と根拠
- ORDレコード
- ord-dfcf9a44669d47df9b47be312338bfd0
- 出典データセット
- uspto-grants-1980_10
- 特許番号
- US04226874
反応ノート
読み込み中…