Hydrogen Bromide → 5-((2-Aminoethyl)thiomethyl)thiazole dihydrobromide
反応式
O[CH2:2][C:3]1[S:7][CH:6]=[N:5][CH:4]=1.Cl.[NH2:9][CH2:10][CH2:11][SH:12].[BrH:13]>>[BrH:13].[BrH:13].[NH2:9][CH2:10][CH2:11][S:12][CH2:2][C:3]1[S:7][CH:6]=[N:5][CH:4]=1参加物
4
実験手順
The reaction of 5-hydroxymethylthiazole (2.01 g.) with cysteamine hydrochloride (1.99 g.) in aqueous hydrobromic acid by the method described in Example 1(i)(a) gave 5-((2-aminoethyl)thiomethyl)thiazole dihydrobromide (4.85 g.) m.p. 191°-194° (from methanol).
出典と根拠
- ORDレコード
- ord-8f36305cd56a4d05b25ffcb6a89e475b
- 出典データセット
- uspto-grants-1980_10
- 特許番号
- US04228291
反応ノート
読み込み中…