Ammonia → N-p-Bromophenylthiourea

HRID 910227

反応式

HRID 910227 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[S:10])=[CH:4][CH:3]=1.[NH3:11]>O1CCCC1>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH2:11])=[S:10])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 222AmmoniaHCID 161334-Bromophenyl isothiocyanate

生成物 1

HCID 2735620N-p-Bromophenylthiourea

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

4-Bromophenylisothiocyanate (21.4 g) was dissolved in tetrahydrofuran (50 mL), and concentrated aqueous ammonia (28%) (13.7 mL) was added dropwise to the solution, followed by stirring at room temperature for 10 minutes. The solvent was concentrated under reduced pressure, and the crystals were recovered through filtration by use of water, followed by recrystallization from ethanol, to thereby yield the title compound (16.4 g).

後処理

  1. concentrationThe solvent was concentrated under reduced pressure
  2. filtrationthe crystals were recovered through filtration by use of water
  3. customfollowed by recrystallization from ethanol

出典と根拠

ORDレコード
ord-21dc0986b22b4059a3b8ea7a202da54c
出典データセット
uspto-grants-2011_09
特許番号
US08022075B2

関連ノート

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