2,6-Dipropylphenol → 2,6-Dipropyl4-propionylphenol

HRID 9250ノート

反応式

HRID 9250 の反応式
[C:1]([O-:5])(=O)[CH2:2][CH3:3].[Na+].[CH2:7]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([CH2:16][CH2:17][CH3:18])[C:11]=1[OH:19])[CH2:8][CH3:9]>OS(C(F)(F)F)(=O)=O>[CH2:16]([C:12]1[CH:13]=[C:14]([C:1](=[O:5])[CH2:2][CH3:3])[CH:15]=[C:10]([CH2:7][CH2:8][CH3:9])[C:11]=1[OH:19])[CH2:17][CH3:18]

参加物

4

反応物 2

HCID 811072,6-DipropylphenolHCID 2723816Sodium Propionate

生成物 1

HCID 113108722,6-Dipropyl4-propionylphenol

試薬・触媒・溶媒 1

HCID 62406Trifluoromethanesulfonic acid溶媒

実験手順

Sodium propanoate (0.88 g, 1.5 eq) and 2,6-dipropylphenol (1.09 g, 1.0 eq) were combined in Triflic Acid (5.0 g) as in Example 13, step 1. The resulting waxy solid was purified by chromatography on silica gel using ethyl acetate:hexanes:acetic acid (10:90:1) to give the titled phenol.

後処理

  1. customThe resulting waxy solid was purified by chromatography on silica gel

出典と根拠

ORDレコード
ord-ec11d9e4f3f449f6a915145c8ea66bec
出典データセット
uspto-grants-2006_08
特許番号
US07091230B2

反応ノート

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