Chloride → Tert-butyl 2-(3-cyano-4-(2-fluoropyridin-4-yl)phenyl)acetate

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:10]2[cH:11][c:12]([F:16])[n:13][cH:14][cH:15]2)[c:6]([C:7]#[N:8])[cH:9]1.[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23]([CH2:24][Zn+:25])=[O:26].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[Cl-:17]>>[c:2]1([CH2:24][C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:26])[cH:3][cH:4][c:5](-[c:10]2[cH:11][c:12]([F:16])[n:13][cH:14][cH:15]2)[c:6]([C:7]#[N:8])[cH:9]1