Phosgene → 2-(2-Chloro-6-nitrophenyl)ethoxycarbonyl chloride
反応式
[C:1]([Cl:4])(Cl)=[O:2].[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:7]=1[CH2:15][CH2:16][OH:17]>C1COCC1>[Cl:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:7]=1[CH2:15][CH2:16][O:17][C:1]([Cl:4])=[O:2]参加物
4
実験手順
Phosgene was introduced in a solution of 2-(2-chloro-6-nitrophenyl)ethanol (31 g, 154 mmol) in THF (190 ml, dist. over CaH2) at room temperature under stirring. After 2.5 h the excess phosgene and the solvent were removed by distillation in a high vacuum. 2-(2-chloro-6-nitrophenyl)ethoxycarbonyl chloride (39.4 g, 97%) was obtained as a yellow oil.
後処理
- customthe solvent were removed by distillation in a high vacuum
出典と根拠
- ORDレコード
- ord-5eea3744c2ce48369a72f21b65a68c3e
- 出典データセット
- uspto-grants-1998_06
- 特許番号
- US05763599
反応ノート
読み込み中…