Triphosgene → HCID 19076265、化合物

HRID 965316ノート

反応式

HRID 965316 の反応式
[NH2:1][N:2]1[CH:10]=[C:8]([CH3:9])[C:6](=[O:7])[NH:5][C:3]1=[O:4].[Cl:11][C:12](Cl)([O:14]C(=O)OC(Cl)(Cl)Cl)Cl>O1CCCC1>[Cl:11][C:12]([NH:1][N:2]1[CH:10]=[C:8]([CH3:9])[C:6](=[O:7])[NH:5][C:3]1=[O:4])=[O:14]

参加物

4

反応物 2

HCID 94429TriphosgeneHCID 118191591-Amino thymine

生成物 1

HCID 19076265HCID 19076265、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

反応条件

温度
0 °C

実験手順

1-Amino thymine (7, 12.5 g, 0.1 mol) is dissolved in tetrahydrofuran (500 mL) and the solution is cooled to 0° C. and a 2M solution of triphosgene in THF (150 mL) is added and the reaction is stirred for 4 hours. The solution is evaporated to a solid, which is used as is in the next reaction.

後処理

  1. customThe solution is evaporated to a solid, which
  2. customas is in the next reaction

出典と根拠

ORDレコード
ord-990b2642976f435da185362129b2b005
出典データセット
uspto-grants-1998_06
特許番号
US05773571

反応ノート

読み込み中…