HCID 10910823、化合物 → Spermine

HRID 968183

反応式

HRID 968183 の反応式
C([CH:8]([CH2:24][CH2:25][NH:26][CH2:27][CH2:28][CH2:29][CH2:30][NH:31][CH2:32][CH2:33][CH2:34][NH2:35])[N:9](C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)(OC(C)(C)C)=O.N(CCCI)=[N+]=[N-]>[Pd]>[NH2:35][CH2:34][CH2:33][CH2:32][NH:31][CH2:30][CH2:29][CH2:28][CH2:27][NH:26][CH2:25][CH2:24][CH2:8][NH2:9]

参加物

4

反応物 2

HCID 10910823HCID 10910823、化合物HCID 22610912TriBoc-Spermine

生成物 1

HCID 1103Spermine

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

Monoquaternary spermine containing hydrophilic head-group was prepared in a similar way to compound 3. Briefly, TriBoc-Spermine was reacted with excess of 1-azido-3-iodo-propane in the presence of excess TBA. The resulting quaternarized derivative was hydrogenised under (Pd—C) and Boc protecting group were removed using gaseous HCl in dry methanol.

後処理

  1. customwere removed

出典と根拠

ORDレコード
ord-7efc57ded6f7404794f1c0a62996d328
出典データセット
uspto-grants-2005_10
特許番号
US06958325B2

関連ノート

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