反応式
C([O-])(=O)CCNC(=O)[C@@H](C(CO)(C)C)O.[CH3:16][C:17]([C@@H:25]([OH:40])[C:26]([NH:28][CH2:29][CH2:30][C:31]([NH:33][C@H:34](C(O)=O)[CH2:35][SH:36])=[O:32])=[O:27])([CH2:19][O:20][P:21]([OH:24])([OH:23])=[O:22])[CH3:18].[P:41]([O:53][CH2:54][C@H:55]1[O:59][C@@H:58]([N:60]2[C:69]3[N:68]=[CH:67][N:66]=[C:64]([NH2:65])[C:63]=3[N:62]=[CH:61]2)[C@H:57]([OH:70])[C@@H:56]1[OH:71])([O:44][P:45]([O:48]P(O)(O)=O)([OH:47])=[O:46])(=[O:43])[OH:42]>>[CH3:18][C:17]([C@@H:25]([OH:40])[C:26]([NH:28][CH2:29][CH2:30][C:31]([NH:33][CH2:34][CH2:35][SH:36])=[O:32])=[O:27])([CH2:19][O:20][P:21]([OH:24])([OH:23])=[O:22])[CH3:16].[CH3:19][C:17]([C@@H:25]([OH:40])[C:26]([NH:28][CH2:29][CH2:30][C:31]([NH:33][CH2:34][CH2:35][SH:36])=[O:32])=[O:27])([CH2:16][O:48][P:45]([O:44][P:41]([O:53][CH2:54][C@H:55]1[O:59][C@@H:58]([N:60]2[C:69]3[N:68]=[CH:67][N:66]=[C:64]([NH2:65])[C:63]=3[N:62]=[CH:61]2)[C@H:57]([OH:70])[C@@H:56]1[OH:71])([OH:42])=[O:43])([OH:47])=[O:46])[CH3:18].[C@@H:58]1([N:60]2[C:69]3[N:68]=[CH:67][N:66]=[C:64]([NH2:65])[C:63]=3[N:62]=[CH:61]2)[O:59][C@H:55]([CH2:54][O:53][P:41]([O:24][P:21]([O:20][CH2:19][C:17]([C@H:25]([C:26]([NH:28][CH2:29][CH2:30][C:31]([NH:33][CH2:34][CH2:35][SH:36])=[O:32])=[O:27])[OH:40])([CH3:16])[CH3:18])([OH:23])=[O:22])([OH:42])=[O:44])[C@@H:56]([O:71][P:21]([OH:23])([OH:22])=[O:20])[C@H:57]1[OH:70]参加物
6
実験手順
Production cells used to produce pantothenate and/or CoA, can be used to express alpha-ketopantoate hydroxymethyltransferase (E.C. 2.1.2.11), alpha-ketopantoate reductase (E.C. 1.1.1.169), and pantothenate synthase (E.C. 6.3.2.1), to produce pantothenate, or in addition pantothenate kinase (E.C. 2.7.1.33), 4′-phosphopantethenoyl-1-cysteine synthetase (E.C. 6.3.2.5), 4′-phosphopantothenoylcysteine decarboxylase (E.C. 4.1.1.36), ATP:4′-phosphopantetheine adenyltransferase (E.C. 2.7.7.3), and dephospho-CoA kinase (E.C. 2.7.1.24), to produce coenzyme A.
出典と根拠
- ORDレコード
- ord-373a300b91f1422e801d275a7e7fb886
- 出典データセット
- uspto-grants-2007_12
- 特許番号
- US07309597B2
関連ノート
読み込み中…