Sodium Carbonate → 5-Methyl-2-phenyl-2-hexenal oxime

HRID 975252

反応式

HRID 975252 の反応式
[CH3:1][CH:2]([CH3:14])[CH2:3][CH:4]=[C:5]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH:6]=O.[Cl-].[OH:16][NH3+:17].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C.O>[CH3:1][CH:2]([CH3:14])[CH2:3][CH:4]=[C:5]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH:6]=[N:17][OH:16]

参加物

6

反応物 3

HCID 10340Sodium CarbonateHCID 21645Hydroxylamine HClHCID 5760265-Methyl-2-phenylhex-2-enal

生成物 1

HCID 867504445-Methyl-2-phenyl-2-hexenal oxime収率 74.7%

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒2 回

実験手順

To a solution of 5-methyl-2-phenyl-2-hexenal (5.0 g, 27 mmol) and hydroxylammonium chloride (3.7 g, 53 mmol) in a mixture of 96% ethanol (20 ml) and water (5 ml) was carefully added a solution of sodium carbonate (11.2 g, 106 mmol) in water (30 ml). The resulting mixture was stirred for 2h, the precipitated compound was filtered off and suspended in dichloromethane (500 ml). The suspension was filtered and the solvent evaporated from the filtrate in vacuo to give 4.1 g of 5-methyl-2-phenyl-2-hexenal oxime.

後処理

  1. filtrationthe precipitated compound was filtered off
  2. filtrationThe suspension was filtered
  3. customthe solvent evaporated from the filtrate in vacuo

出典と根拠

ORDレコード
ord-f1f4eae056ee4b13a00afc32e58d3f69
出典データセット
uspto-grants-1997_03
特許番号
US05608069

関連ノート

読み込み中…