Trifluoroacetic acid → (Benzyloxy)(methyl)amine

HRID 976632

反応式

HRID 976632 の反応式
C(O[C:6](=O)[N:7]([O:12][CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)CC(C)C)(C)(C)C.C(ON(C)C(=O)OC(C)(C)C)C1C=CC=CC=1.FC(F)(F)C(O)=O>>[CH2:13]([O:12][NH:7][CH3:6])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

4

反応物 3

HCID 6422Trifluoroacetic acidHCID 14227181tert-butyl N-benzyloxy-N-methylcarbamateHCID 19967428tert-butyl N-benzyloxy-N-(2-methylpropyl)carbamate

生成物 1

HCID 13417387(Benzyloxy)(methyl)amine

実験手順

Using the general method of Compound 54 Part C, tert-butyl N-benzyloxy-N-methylcarbamate (3.0 g, 13 mmol) was reacted with trifluoroacetic acid (10 mL, 130 mmol) to provide 1.58 g of N-benzyloxy-N-methylamine as a yellow oil.

出典と根拠

ORDレコード
ord-dfca262cc7444a829f0c340430c1b57e
出典データセット
uspto-grants-1997_03
特許番号
US05612377

関連ノート

読み込み中…