Benzyl Alcohol → 1,5-Pentanedioic Acid Monobenzyl Ester
反応式
[C:1]1(=[O:8])[O:7][C:5](=[O:6])[CH2:4][CH2:3][CH2:2]1.[CH2:9]([OH:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C1(C)C=CC=CC=1>[CH2:9]([O:16][C:5]([CH2:4][CH2:3][CH2:2][C:1]([OH:7])=[O:8])=[O:6])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1参加物
4
反応条件
- 温度
- 70 °C
実験手順
A mixture of glutaric anhydride (11.4 g, 0.1 mol) and benzyl alcohol (11.4 mL, 1.1 equiv.) in toluene (200 mL) was heated at 70° C. for 2 days. Solvent was evaporated at reduced pressure to give the product which was dried under high vacuum and was pure enough to use in the next step. 1H NMR (CDCl3): δ1.96 (t, J=7.2 Hz, 2H), 2.44 (q, J=7.0 Hz, 4H), 5.13 (s, 2H), 7.33 (s, 5H).
後処理
- customSolvent was evaporated at reduced pressure
- customto give the product which
- customwas dried under high vacuum
出典と根拠
- ORDレコード
- ord-4e290f5e087f42ef88f7fe678145204a
- 出典データセット
- uspto-grants-2002_10
- 特許番号
- US06469065B1
反応ノート
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