기본 정보
- 표준 SMILES
FCC1CO1- InChIKey
OIFAHDAXIUURLN-UHFFFAOYSA-N- 분자식
- C3H5FO
- 평균 분자량
- 76.07 g/mol
- 단동위원소 질량
- 76.032443
개요
Epifluorohydrin is a clear colorless liquid. (NTP, 1992)
이름 및 식별자
- 우선 이름
- 1,2-Epoxy-3-fluoropropane
- IUPAC
- 2-(fluoromethyl)oxirane
- 영어명
- Epifluorohydrin
- 분자식
- C3H5FO
- 분자량
- 76.07
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
503-09-3- PubChem CID
- 10418
- DTXSID
DTXSID4025244- UNII
- 0ZZ4ROH5IL
- EC Number
- 207-960-1
- Nikkaji
- J1.567I
물성
구조 계산 물성
- XLogP
- -0.2
- 극성 표면적
- 12.5 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 1
- 무거운 원자 수
- 5
- 형식 전하
- 0
- 복잡도
- 37.9
실험 및 물리화학적 성질
물리화학적 성질
- 끓는 점
- 85 · 85-86 °C (lit.)
- 밀도
- 1.067 g/mL · 1.067 g/mL at 25 °C (lit.)
- 굴절률
- 20 · n20/D 1.368(lit.)
- 인화점
- 40 °F · 40 °F
- 저장 조건
- 0 · 0-6°C
- 물리적 상태
- 액체
- 색상
- 투명한
- InChI
- InChI=1S/C3H5FO/c4-1-3-2-5-3/h3H,1-2H2
- InChIKey
- OIFAHDAXIUURLN-UHFFFAOYSA-N
- SMILES
- O1CC1CF
- NIST
- Oxirane, (fluoromethyl)-(503-09-3)
- EPA
- Epifluorohydrin (503-09-3)
화학적 성질
clear colourless liquid
안전 및 규제
GHS 분류
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P361+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Reactivity Profile
A halogenated epoxide. Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. The chlorinated derivative has been shown to be incompatible with aniline, strong oxidizers, sulfuric acid, isopropylamine, zinc, aluminum, iron, etc. see epichlorohydrin.
안전 및 보호
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Personal Protective Equipment (PPE)
RECOMMENDED RESPIRATOR: When working with this chemical, wear a NIOSH-approved full face chemical cartridge respirator equipped with the appropriate organic vapor cartridges. If that is not available, a half face respirator similarly equipped plus airtight goggles can be substituted. However, please note that half face respirators provide a substantially lower level of protection than do full face respirators. (NTP, 1992)
안전 데이터
- wgk
- 3
- rtecs
- TZ3325000
- ridadr
- UN 2924 3/PG 2
- HS 번호
- 2910900090
- risk_code
- 11-23/24/25-34
- hazard_code
- F,T
- safety_code
- 16-26-45-38-36/37/39-33
- 포장분류
- I
- 위험 등급
- 6.1(a)
- 위험 참고 사항
- Flammable/Highly Toxic
- Hazard Classifications
- Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralFlam. Liq. 2Skin Corr. 1B
- 스토리지 클래스
- 3 - Flammable liquids
화학 및 산업
응용 분야
용도Epifluorohydrin is used as a reagent in the synthesis of N-arylphosphoramidates. In addition, it is used in the synthesis of orally bioavailable ALK inhibitors in the treatment of tumors.
일반 설명Clear colorless liquid.
상·하류 제품 정보
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