뉴트랄레드

Neutral Red

HCID 11105CAS 553-24-2

기본 정보

표준 SMILES
Cc1cc2nc3ccc(N(C)C)cc3nc2cc1N.Cl
InChIKey
PGSADBUBUOPOJS-UHFFFAOYSA-N
분자식
C15H16N4.ClH
평균 분자량
288.77 g/mol
단동위원소 질량
288.11417422

개요

Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).

이름 및 식별자

우선 이름
Neutral Red
IUPAC
8-N,8-N,3-trimethylphenazine-2,8-diamine;hydrochloride
현지명
뉴트랄레드
영어명
Neutral Red
분자식
C15H16N4.ClH
분자량
288.78

이름 및 동의어

NEUTRAL RED553-24-2Toluylene Red3-Amino-7-dimethylamino-2-methylphenazine hydrochlorideC.I. Basic Red 5Neutral Red chlorideMichrome No. 226Neutral Red W2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochlorideC.I. 50040Cerven neutralniCerven toluylenova
이름 더 보기
C.I.베이직레드5C.I.베이직레드5,모노수화염화물N8,N8,3-트리메틸-2,8-페아진디아민모노수화염화물톨루일엔레드2,8-페아진디아민,N8,N8,3-트리메틸-,모노수화염화물뉴트랄레드아미노디메틸-아미노톨루아미노진수화염화물Basic Red 5N2,N2,7-TriMethylphenazine-2,8-diaMine hydrochlorideKernechrotneutralredwc.i.basicred5michromeno.226cervenneutralnicervenzasadita5
C.I. Basic Red 5, monohydrochlorideCerven zasadita 5Aminodimethylaminotoluaminozine hydrochlorideNuclear Fast Red (basic dye)AI3-60242261QK3SSBHNSC-3092CHEBI:86370

데이터베이스 식별자

CAS
553-24-2
PubChem CID
11105
DTXSID
DTXSID90883440
ChEBI
CHEBI:86370
UNII
261QK3SSBH
EC Number
209-035-8

물성

구조 계산 물성

극성 표면적
55 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
4
회전 가능 결합 수
1
무거운 원자 수
20

실험 및 물리화학적 성질

Chemical ClassesDyes -> Azine Dyes
Physical DescriptionDark green solid; [Merck Index]

물리화학적 성질

녹는점
290 °C · 290 °C (dec.) (lit.)
끓는 점
441.31 °C · 441.31°C (rough estimate)
밀도
1.159 · 1.1590 (rough estimate)
굴절률
1.611 · 1.6110 (estimate)
저장 조건
5 °C · Store at +5°C to +30°C.
용해도
2 O: · H2O: 용해성10mg/mL

화학적 성질

dark green powder

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 11.1% (2 of 18) of reports.

Warning

H315 (77.8%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 18 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Chemical: 2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochloride

Phenazine, 3-amino-7-(dimethylamino)-2-methyl-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryA skin, eye, and respiratory tract irritant; [MSDSonline]
Hazard Classes and CategoriesSkin Irrit. 2 (77.8%)

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
SG1400000
독성
LD50 intraperitoneal in mouse: 432mg/kg
HS 번호
32041300
risk_code
68-36/37/38

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.

용도 및 제조

UsesUsed as an indicator, biological stain, and drug; [ChemIDplus] Used to prepare neutral-red paper; [Merck Index] Azine dye; [Kirk-Othmer]
General Manufacturing Information2,8-Phenazinediamine, N8,N8,3-trimethyl-, hydrochloride (1:1): ACTIVE

응용 분야

용도Neutral Red is a common histology stain used to determine cell viability. It is also used as indicator for nitrogen determination; pH indicator; Dyes and metabolites.

일반 설명Neutral red (C.I. 50040) is a protonated diaminophenazine dye. It is aminodimethylaminomethylphenazinehydrochloride, C15H17N4Cl.

제조 방법

(a) N,N-dimethyl-4-nitrosobenzenamineand 4-Methylbenzene-1,3-diaminereaction, form Toluylene Blue (Basic Dye, C.I. 49410), heating make cyclization; (b) oxidation N1,N1-dimethylbenzene-1,4-diamine, and 4-Methylbenzene-1,3-diamine mixture.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
武汉科美沃化工有限公司+86-2785736489 +8618171418573 · [email protected]
추가 설명 · 1건

정의ChEBI: Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).

관련 반응

3건

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