기본 정보
- 표준 SMILES
Cc1cc2nc3ccc(N(C)C)cc3nc2cc1N.Cl- InChIKey
PGSADBUBUOPOJS-UHFFFAOYSA-N- 분자식
- C15H16N4.ClH
- 평균 분자량
- 288.77 g/mol
- 단동위원소 질량
- 288.11417422
개요
Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).
이름 및 식별자
- 우선 이름
- Neutral Red
- IUPAC
- 8-N,8-N,3-trimethylphenazine-2,8-diamine;hydrochloride
- 현지명
- 뉴트랄레드
- 영어명
- Neutral Red
- 분자식
- C15H16N4.ClH
- 분자량
- 288.78
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
553-24-2- PubChem CID
- 11105
- DTXSID
DTXSID90883440- ChEBI
CHEBI:86370- UNII
- 261QK3SSBH
- EC Number
- 209-035-8
물성
구조 계산 물성
- 극성 표면적
- 55 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 4
- 회전 가능 결합 수
- 1
- 무거운 원자 수
- 20
- 형식 전하
- 0
- 복잡도
- 319
실험 및 물리화학적 성질
물리화학적 성질
- 녹는점
- 290 °C · 290 °C (dec.) (lit.)
- 끓는 점
- 441.31 °C · 441.31°C (rough estimate)
- 밀도
- 1.159 · 1.1590 (rough estimate)
- 굴절률
- 1.611 · 1.6110 (estimate)
- 저장 조건
- 5 °C · Store at +5°C to +30°C.
- 용해도
- 2 O: · H2O: 용해성10mg/mL
- 산도 계수 (pKa)
- 6.7 · 6.7, 7.4(at 25℃)
- 물리적 상태
- 고체
- 색상
- 매우 진한 녹색
- 수소이온지수(pH)
- 3.1 · 3.1 (10g/l, H2O, 20℃)
- 냄새
- 냄새 없는
- 수용성
- 50 g/L · 50g/L
- Merck
- 14 · 14,6488
- BRN
- 3918740 · 3918740
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- 주요 응용
- 연료 전지 발전 시스템, 액정 디스플레이, 태양 전지, 센서, 열변색 소재, 목재 착색제, 세제, 담배 연기 분석, 화장품, 세균 감염 탐지, 다제내성 억제제, 화상 치료, 치내 치료, 당뇨병, 비만, 암, 연령 관련 황반변성, 바이러스성 질환
- InChI
- 1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H
- InChIKey
- PGSADBUBUOPOJS-UHFFFAOYSA-N
- SMILES
- Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1
- EPA
- Neutral Red (553-24-2)
화학적 성질
dark green powder
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 11.1% (2 of 18) of reports.
Warning
H315 (77.8%): Causes skin irritation [Warning Skin corrosion/irritation]
P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 18 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Regulatory Information
Chemical: 2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochloride
Phenazine, 3-amino-7-(dimethylamino)-2-methyl-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
안전 데이터
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- SG1400000
- 독성
- LD50 intraperitoneal in mouse: 432mg/kg
- HS 번호
- 32041300
- risk_code
- 68-36/37/38
- hazard_code
- Xn,Xi
- safety_code
- 36/37-37/39-36-26-24/25
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
용도 및 제조
응용 분야
용도Neutral Red is a common histology stain used to determine cell viability. It is also used as indicator for nitrogen determination; pH indicator; Dyes and metabolites.
일반 설명Neutral red (C.I. 50040) is a protonated diaminophenazine dye. It is aminodimethylaminomethylphenazinehydrochloride, C15H17N4Cl.
제조 방법
(a) N,N-dimethyl-4-nitrosobenzenamineand 4-Methylbenzene-1,3-diaminereaction, form Toluylene Blue (Basic Dye, C.I. 49410), heating make cyclization; (b) oxidation N1,N1-dimethylbenzene-1,4-diamine, and 4-Methylbenzene-1,3-diamine mixture.
상·하류 제품 정보
상류 원료
공급사50 곳
추가 설명
정의ChEBI: Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).
관련 반응
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