기본 정보
- 표준 SMILES
O=c1c2ccccc2[nH]c2cc3c(=O)c4ccccc4[nH]c3cc12- InChIKey
NRCMAYZCPIVABH-UHFFFAOYSA-N- 분자식
- C20H12N2O2
- 평균 분자량
- 312.3 g/mol
- 단동위원소 질량
- 312.08987762
개요
Quinacridone is an organonitrogen heterocyclic compound and an organic heterotetracyclic compound.
이름 및 식별자
- 우선 이름
- Quinacridone
- IUPAC
- 5,12-dihydroquinolino[2,3-b]acridine-7,14-dione
- 현지명
- C.I. 색소 VI올ET 19
- 영어명
- Quinacridone
- 분자식
- C20H12N2O2
- 분자량
- 312.32
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
1047-16-1- PubChem CID
- 13976
- DTXSID
DTXSID5027354- ChEBI
CHEBI:174977- UNII
- 11P487375P
- EC Number
- 213-879-2
- Nikkaji
- J8.584G
물성
구조 계산 물성
- XLogP
- 4
- 극성 표면적
- 58.2 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 4
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 24
- 형식 전하
- 0
- 복잡도
- 500
실험 및 물리화학적 성질
Polymers
Plastics -> Polyolefin-I; PUR; Polyolefin-II; PVC (soft); ABS; PVC (rigid); PET; PMMA; PA; PC; (E)PS
Plastics -> Pigments agents
Color/Form
Red to violet solid with blueish or yellowish tint depending upon crystalline form.
particle characteristics: thin plates
Solubility
Insoluble in water
Insoluble in organic solvents and dispersion media.
Food Contact Substances
FCS -> FDA Cumulative Estimated Daily Intake (CEDI)
FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
FCS -> FDA Inventory of Effective Food Contact Substance (FCS) Notifications
FCS -> FDA Inventory of Effective Food Contact Substance (FCS) Notifications
Physical Description
Liquid; Other Solid; Dry Powder; Other Solid; CBI
Red to violet solid; Bluish or yellowish tint depending of form; [HSDB] Red odorless powder; [MSDSonline]
Solid
물리화학적 성질
- 녹는점
- 390 °C · 390 °C
- 끓는 점
- 568.5 · 568.5±50.0 °C(Predicted)
- 밀도
- 1.5 g/cm3 · 1.5 g/cm3
- 저장 조건
- Sealed in dry,Room Temperature
- 물리적 상태
- Solid:nanomaterial
- 산도 계수 (pKa)
- -2.96 · -2.96±0.20(Predicted)
- 색상
- Orange to Amber to Dark red
- 화장품 원료 기능
- 색소머리 염색
- LogP
- 2.2 at · 2.2 at 24℃ and pH7
- NIST
- 2 · Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-(1047-16-1)
- EPA
- Quinacridone (1047-16-1)
화학적 성질
The parent compound Pigment Violet 19 exists in three polymorphic modifications. The red gamma and violet beta forms are commercial pigments, whereas the red alpha form is metastable.
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 99.6% (760 of 763) of all reports.
Not Classified
Aggregated GHS information provided per 763 reports by companies from 4 notifications to the ECHA C&L Inventory.
유해성 정보
Regulatory Information
Chemical: Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-
Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 23-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14755
Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Skin reactions have been reported: inflammation in a tattoo after sun exposure and acne-like changes on the face of a child colored with a red felt-tip pen; Also acne-like reaction on the skin of rabbits after coloring with red felt-tip pen; [HSDB] No known adverse effects on human health; Not an irritant; Not a sensitizer; [MSDSonline] See Acridine.
Special Reports
A BRIEF DESCRIPTION OF THE CHEMICAL PROPERTIES, DEVELOPMENT, & EFFORTS TOWARD GAINING APPROVAL OF THE QUINACRIDONE PIGMENT VIOLET #19 (LINEAR TRANS QUINACRIDONE) BY THE FDA IS PRESENTED.[VIOLET #19--POTENTIAL NEW COSMETIC COLOR; COSMET TOILET 94(MAY) 19 (1979)]
[ITC/USEPA; Information Review #315 (Draft) Cinquasia Red 1982]
독성 정보
Environmental Fate
Much of cinquasia red will be bound up in the components of landfills, junkyards, and general dump sites.
Terrestrial: The insolubility of cinquasia red will cause it to collect in soils and sediments.
Aquatic: Due to its insolubility, cinquasia red may reside in the water column for a substantial period, long enough to become part of deep sea sediments.
Human Toxicity Excerpts
Two different red pigments used for tattooing were found to give rise to inflammatory reactions in the skin. No inorganic component was found in the pigments. NMR and MS analyses elucidated the molecular structures ... a red-violet pigment was found to be linear quinacridone. A strong exposure to UV-light was reported in most cases prior to the onset of the inflammation.
Acne-like changes were observed on a child's cheek after coloring them with a red felt tip pen. Numerous comedos appeared around a red tattoo colored with felt tip pen ink on a 16-yr-old girl.
Artificial Pollution Sources
Released to the environment as fugitive dust during manufacturing and end use.
EPA reported that the waste streams from the manufacture of cinquasia red are brines which contain small amounts of organic chemicals and strong acid wastes.
Non-Human Toxicity Excerpts
Pigment Violet #19 was nonmutagenic by Ames test.
In rabbits ... /pigment violet 19/ in felt tip pens produced a comedo type reaction.
규제 정보
안전 데이터
- tsca
- TSCA listed
- rtecs
- VA8533500
- 독성
- LD50 oral in rat: > 20mL/kg
- HS 번호
- 29339900
- safety_code
- 24/25
- 기존화학 물질
- KE-10744
- 유해 물질 데이터
- 1047-16-1(Hazardous Substances Data)
화학 및 산업
약리 정보
용도 및 제조
Uses
Used as pigment (paints, printing inks, plastics, rubber, alkyd resin enamels, textile emulsion inks, textiles, nitrocellulose, vinyl, and acrylic lacquers) and sensitizing dye in color photo electrophoresis; Used to tone and make other pigments; [HSDB]
Painting (Pigments, Binders, and Biocides) [Category: Paint]
PAINTS, PRINTING INKS, PLASTICS, RUBBER
Cinquasia red is used a sensitizing dye in color photoelectrophoresis.
Pigment in textiles
As colorants for plastics, quinacridone pigments may be used in all resins except nylon-66 and polystyrene./Quinacridone Pigments/
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) 2.49X10+7 GRAMS (PRINCPL CUSTMS DISTS)
(1981) 6.21X10+6 GRAMS (PRINCPL CUSTMS DISTS)
U.S. Production
2023: 1,000,000 - <2,500,000 lb
1.2 million lbs.
(1979) 7.11X10+8 GRAMS
(1981) 6.25X10+8 GRAMS
Consumption Patterns
Quinacridone pigment use in automotive finishes accounts for the majority of the consumption of cinquasia red, with lesser quantities finding end uses in PVC manufacturing and the textile industry.
ESSENTIALLY 100% AS A PIGMENT
Methods of Manufacturing
The major commercial production methods involve cyclization of 2,5-di(arylamino)terephthalic acids and esters.
The manufacturing process /of cinquasia red/ required three steps: (1) halogenation of terephthalic acid, (2) reaction of aniline with 2,5-dihaloterephthalic acid, and (3) cyclization of 2,5-dianilinoterephthalic acid to finished pigment.
HEATING OF DIALKYL(C1-C3)-2,5-DIARYLAMINO-3,6-DIHYDROTEREPHTHALATE IN AN INERT, HIGH-BOILING MEDIUM FOLLOWED BY OXIDATION
Use Classification
Plastics -> Polymer Type -> Polyolefin-I; PUR; Polyolefin-II; PVC (soft); ABS; PVC (rigid); PET; PMMA; PA; PC; (E)PS
Plastics -> Pigments agents
Cosmetics -> Hair dyeing; Cosmetic colorant
General Manufacturing Information
Synthetic Dye and Pigment Manufacturing
Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-: ACTIVE
Importer: American Hoechst Corporation, Rte 202-206 North, Bridgewater, NJ, 08876
Importer: Dainippon Ink & Chems. America Inc., 200 Park Avenue, New York, NY, 10017
Importer: BASF Wyandotte Corp., 100 Cherry Hill Rd., Parsippany, NJ, 07054.
상·하류 제품 정보
상류 원료
하류 제품
공급사50 곳
추가 설명
정의A lightfast pigment used in paints, printing inks, plastics, etc.
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