Methyltrimethoxysilane
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1185-55-3CO[Si](C)(OC)OCBFXIKLCIZHOAAZ-UHFFFAOYSA-NSee also: Silane, trimethoxymethyl-, homopolymer (annotation moved to).
1185-55-3、25498-02-6DTXSID3027370CHEMBL3182654Liquid; Liquid; Other Solid; CBI
Colorless liquid; [Sigma-Aldrich MSDS]
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
This chemical does not meet GHS hazard criteria for 1.7% (22 of 1271) of reports.
Danger
H225 (97.6%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P272, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 1271 reports by companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
Chemical: Silane, trimethoxymethyl-
Silane, trimethoxymethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Silane, trimethoxymethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 17-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14707
Silane, trimethoxymethyl-: Does not have an individual approval but may be used under an appropriate group standard
Shown to be a skin sensitizer in guinea pigs using a modified Buehler method at 25% in PEG 300 without adjuvant (grade 1 skin reactions in 30% and 20% of the animals after 24 and 48 hours, respectively); [EPA - TSCATS] A mild skin and eye irritant; [RTECS] An eye irritant; [Sigma-Aldrich MSDS] 1185-55-3 AND (sensitizer OR sensitization OR allergic): no results; [PubMed] See Trimethoxysilane and Methyl silicate.
Used in household products for conditioning and waterproofing leather; [REPROTOX]
The uses of Methyltrimethoxysilane (MTMS) include as a coupling agent in thermoplastics and thermosetting resins, a cross-linker in silicone sealants, a water repellent component, and in silicone hard-coats for plastics.
Petrochemical Manufacturing
Silane, trimethoxymethyl-: ACTIVE
용도실리콘 고무 및 유리 섬유 표면 처리제의 가교제로서 기계적 강도.
개요Trimethoxy (methyl) silane is an organosilicon compound. It can be used as a crosslinker in the preparation of polysiloxane polymers. It can also be used as an acid scavenge used in the formation of substituted azulenes from allenylsilanes and tropylium tetrafluoroborate. It can also be used as the precursor for synthesis of flexible silica aerogels.
용도Methyltrimethoxysilane(MTMS) in combination with iron nitrate altered the pore structure dramatically. As the Crosslinking agent of RTV silicone rubber and glass fiber surface treatment agent and talk to agents outside of reinforced plastic laminated products in order to improve the mechanical strength, heat resistance, moisture resistance. Methyltrimethoxysilane is used as an acid scavenger, for example in the formation of substituted azulenes from allenylsilanes and tropyl-ium tetrafluoroborate.
일반 설명Trimethoxymethylsilane (MTM) is an organosilicon compound widely used as a precursor for the preparation of silica-based materials, which finds the applications in various fields. Particularly in molecular assembly, linking nano building blocks, and selective synthesis oligosiloxane compounds. It can also be utilized as a crosslinker in the synthesis of polysiloxane polymers.
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Colorless clear liquid
Flam. Liq. 2 (97.6%)
Flam. Liq. 2 (33.3%)
Flammable liquids - Category 2
35 [mg/m3]
390 [mg/m3]
2300 [mg/m3]
The No Observed Adverse Effect Level (NOAEL) of 100 ppm (557 mg/m3) from the 90-day inhalation rat study was considered the point of departure for the health-based Workplace Environmental Exposure Limit (WEEL) derivation. After adjusting for duration of exposure and interindividual variability, the 8-hour Time-Weighted Average (TWA) WEEL value of 10 ppm (55 mg/m3) is fully expected to provide a significant margin of safety against potential adverse health effects in workers.
Studies showed a low order of acute toxicity for MTMS. MTMS was slightly irritating to both eyes and skin in rabbits, and a weight of evidence assessment supports that MTMS is not a dermal sensitizer. In vitro and in vivo assays indicated MTMS has a low potential for genotoxicity. MTMS did not produce any changes in reproductive or developmental parameters in a rat study. In a 90-day inhalation study in rats, MTMS was associated with urinary bladder epithelial hyperplasia, calculi formation, and moderate kidney dilation with hyperplasia of the pelvic epithelium and granulomatous inflammation; however, an expert panel review concluded that changes in the bladder and kidney were adaptive responses to a physical or chemical irritant present within the urine and were not considered to represent a preneoplastic change.
Methyltrimethoxysilane is usually prepared from methyltrichlorosilane and methanol:CH3SiCl3 + 3 CH3OH → CH3Si(OCH3)3 + 3 HCl