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Cosmetic ingredients (Ammonium Lactate) -> CIR (Cosmetic Ingredient Review)

Buffering

FDA approved drugs -> Active ingredient

FDA approved drugs -> Active ingredient

Ammonium lactate appears as white solid or liquid. Has no odor. Sinks and mixes with water. (USCG, 1999)

Liquid; Liquid; Other Solid

White solid or liquid; Odorless; [CHRIS] 68-72% Aqueous solution: Light yellow liquid; [PURAC Bioquimica MSDS]

This chemical does not meet GHS hazard criteria for 87.6% (415 of 474) of all reports.

Warning

H315 (12.2%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 474 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

Chemical: Propanoic acid, 2-hydroxy-, monoammonium salt

Propanoic acid, 2-hydroxy-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanoic acid, 2-hydroxy-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Ammonium lactate: Does not have an individual approval but may be used under an appropriate group standard

Causes tremors, muscle weakness, and altered gastric secretion in acute oral studies of cattle; [RTECS] A skin, eye, nose, and throat irritant; Harmful by ingestion; [CHRIS] Not to be used in infant foods; [JECFA] Not considered to pose any health hazards; [PURAC Bioquimica MSDS]

Acidic salts, such as AMMONIUM LACTATE, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Skin Irrit. 2 (12.2%)

Eye Irrit. 2 (100%)

12 [mg/m3]

130 [mg/m3]

790 [mg/m3]

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Ammonium Lactate...

Safe for use in cosmetics, with qualifications

Lactic acid is an alpha-hydroxy acid. It is a normal constituent of tissues and blood. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. This property may influence hydration of the stratum corneum. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion.

67M901L9NQ

AMMONIUM LACTATE

Established Pharmacologic Class [EPC] - alpha-Hydroxy Acid

Chemical Structure [CS] - Hydroxy Acids

Ammonium lactate is an alpha-Hydroxy Acid.

AMMONIUM LACTATE

CIR ingredient: Ammonium Lactate

Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used in skin moisturizers; [ExPub: TERIS] Used to regulate acidity in foods and to treat flour; [JECFA] Used as an additive to cosmetics and specialty chemical; [PURAC Bioquimica MSDS]

Food Additives -> ACIDITY_REGULATOR; FLOUR_TREATMENT_AGENT -> JECFA Functional Classes

Cosmetics -> Buffering

All Other Chemical Product and Preparation Manufacturing

Propanoic acid, 2-hydroxy-, ammonium salt (1:1): ACTIVE