Tetraethylammonium Bromide (HCID 6285)

개요

See also: Tetraethylammonium (has active moiety).

이름 및 식별자

우선 이름: Tetraethylammonium Bromide
IUPAC: tetraethylazanium bromide
현지명: 브롬화테트라에틸암모늄
영어명: Tetraethylammonium bromide
분자식: C8H20BrN
분자량: 210.16

이름 및 동의어

TETRAETHYLAMMONIUM BROMIDE71-91-0TEABSympatektomanEtambroEthylonBromethylTetraniumBeparonEtamonEtylonTeamon

이름 더 보기

브롬화테트라에틸암모늄테트라에틸암모늄브롬화물테트라에틸암모늄브로마이드테트라에틸암모늄브롬화물테트릴암모늄브로마이드tetraethylazanium bromideTetra ethyl ammonium bromide SolidEthanaminium, N,N,N-triethyl-, bromide (1:1)tmd10

Tetrylammonium bromideTEA bromideTetraethyl ammonium bromideEthanaminium, N,N,N-triethyl-, bromideBromuro de tetrilamonioBromure de tetrylammoniumTMD 10Bromure de tetraethylammonium

데이터베이스 식별자

CAS: 71-91-0
PubChem CID: 6285
DTXSID: DTXSID9044457
ChEMBL: CHEMBL324254
UNII: 0435621Z3N
EC Number: 200-769-4

물성

구조 계산 물성

극성 표면적: 0 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 1
회전 가능 결합 수: 4
무거운 원자 수: 10
형식 전하: 0
복잡도: 47.5

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Quaternary Amines

Density1.39 @ 20°C

Vapor Pressure0.00000079 [mmHg]

Physical Description · 2건

Liquid

Deliquescent solid; [Merck Index] Colorless crystalline solid; Highly hygroscopic; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점: 285 °C · 285 °C (dec.)(lit.)
끓는 점: 310 °C/979.1 · >310 °C/979.1 hPa
밀도: 1 · 1,397 g/cm3
증기 밀도: 5.3 · 5.3 (vs air)
증기압: 1 hPa · <1 hPa
굴절률: 1 · 1,442-1,444
저장 조건: 30 °C · Store below +30°C.
용해도: 0.1 g/mL · 아세토니트릴: 0.1 g/mL 따뜻하고 투명하며 무색
물리적 상태: 액체
색상: 흰색에서 크림색으로
냄새: 냄새 없는
수소이온지수(pH): 6.5 · 6.5 (100g/l, H2O, 20℃)
수용성: 2795 g/L · 2795g/L(25℃)
Merck: 14 · 14,9199
BRN: 3563430 · 3563430
안정성: 안정적인. 강한 산화제와 호환되지 않습니다.
InChI: 1S/C8H20N.BrH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChIKey: HWCKGOZZJDHMNC-UHFFFAOYSA-M
SMILES: [Br-].CC[N+](CC)(CC)CC
NIST: Tetraethylammonium bromide(71-91-0)
EPA: Ethanaminium, N,N,N-triethyl-, bromide (71-91-0)

화학적 성질

white to light yellow crystalline solid

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 1.6% (5 of 317) of reports.

Warning

H302 (18.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 317 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

유해성 정보

Regulatory Information · 4건

Chemical: Ethanaminium, N,N,N-triethyl-, bromide

Ethanaminium, N,N,N-triethyl-, bromide (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanaminium, N,N,N-triethyl-, bromide (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/19226

Tetraethylammonium bromide: HSNO Approval: HSR006306 Approved with controls

Other Safety InformationIMAP assessments - Tetraethylammonium salts: Human health tier II assessment

Hazards Summary · 1건

Causes mydriasis, tremor, and changes in motor activity in acute intraperitoneal studies of mice; Causes ganglion blockage and lowered blood pressure in acute intravenous studies of cats; [RTECS] A skin and strong eye irritant; Targets the heart and CNS; [Sigma-Aldrich MSDS]

Hazard Classes and Categories · 2건

Acute Tox. 4 (18.3%)

Eye irritation - category 2B

안전 및 보호

Protective Action Criteria (PAC) · 3건

8.4 [mg/m3]

92 [mg/m3]

550 [mg/m3]

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: BS5950000
HS 번호: 29239000
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36-37/39
기존화학 물질: KE-34221
F 고인화성물질: 3
Hazard Classifications: Aquatic Chronic 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

약리 정보

MeSH Pharmacological ClassificationA class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.

용도 및 제조

UsesA ganglion blocking agent; [Merck Index]

U.S. Production2023: 1,000,000 - <5,000,000 lb

Industry UsesIntermediate

General Manufacturing Information · 2건

All Other Basic Organic Chemical Manufacturing

Ethanaminium, N,N,N-triethyl-, bromide (1:1): ACTIVE

응용 분야 · 2건

용도Tetraethylammonium Bromide, can be used as a source of tetraethylammonium ions for various pharmaceutical studies. It has also the ability to block K+ channels in various tissues.

일반 설명The use of ion-pairing reagents as mobile phase additives allows the separation of ionic and highly polar substances on reversed phase HPLC columns. The purity of mobile phase additives is of utmost importance to their successful application. Sigma-Aldrich offers an outstanding range of tailor-made reagents for anionic (quaternary ammonium and phosphonium salts) and cationic (alkanesulfonates) determination. All mobile phase additives are subject to rigorous testing with special emphasis on the requirements of modern reversed phase HPLC: