Mops (HCID 70807)｜Huagongshe

이름 및 식별자

우선 이름: Mops
IUPAC: 3-morpholin-4-ylpropane-1-sulfonic acid
현지명: 3-모르폴리노프로판술폰산
영어명: MOPS
분자식: C7H15NO4S
분자량: 209.26

이름 및 동의어

MOPS1132-61-23-Morpholinopropanesulfonic acid4-Morpholinepropanesulfonic acid3-(N-Morpholino)propanesulfonic acidMorpholinopropane sulfonic acid3-morpholin-4-ylpropane-1-sulfonic acidMorpholinopropanesulfonic acidDTXSID4044371273BP63NV3DTXCID2024371CHEBI:44115

이름 더 보기

3-모르폴리노프로판술폰산MOPS FREE ACID4-propanesulfonyl morpholine3-Morpholinopropanesulfoinc Acid4-morpholinopropanesulphonic acid3-MORPHOLINOPROPANESULPHONIC ACID

RefChem:926116morpholine propanesulphonic acidCHEBI:39074214-478-53-Morpholinopropane-1-sulfonic acid3-(morpholin-4-yl)propane-1-sulfonic acid3[N-MORPHOLINO]PROPANE SULFONIC ACIDMFCD00006183

데이터베이스 식별자

CAS: 1132-61-2
PubChem CID: 70807
DTXSID: DTXSID4044371
ChEMBL: CHEMBL1234443
ChEBI: CHEBI:44115
UNII: 273BP63NV3
EC Number: 214-478-5
Nikkaji: J7.270B

물성

구조 계산 물성

XLogP: -3.1
극성 표면적: 75.2 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 5
회전 가능 결합 수: 4
무거운 원자 수: 13
형식 전하: 0
복잡도: 227

실험 및 물리화학적 성질

Physical DescriptionWhite solid; [Merck Index] White odorless powder; [Caledon Laboratories MSDS]

Collision Cross Section · 1건

142.7 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID4044371]；149.5 Å² [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID4044371]；154.6 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID4044371]；142.4 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID4044371]

물리화학적 성질

녹는점: 277 · 277-282 °C
밀도: 1.3168 · 1.3168 (rough estimate)
증기압: 0 Pa · 0Pa at 25℃
굴절률: 1.637 · 1.6370 (estimate)
인화점: 116 °C · 116 °C
저장 조건: room temp
용해도: 2 O: · H2O: 1 M at 20 °C, 투명
물리적 상태: 분말/고체
색상: 하얀색
수소이온지수(pH): 2.5 · 2.5-4.0 (25℃, 1M in H2O)
산도 계수 (pKa): 7.2 · 7.2(at 25℃)
냄새: 냄새 없는
생물학적 소스: synthetic
수용성: 1000 g/L · 1000g/L(20℃)
Merck: 14 · 14,6265
BRN: 1106776 · 1106776
안정성: 안정적인. 강염기, 강산화제와 호환되지 않습니다.
화장품 원료 기능: 버퍼링피부의 멜라닌 생성을 줄입니다
InChI: 1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
InChIKey: DVLFYONBTKHTER-UHFFFAOYSA-N
SMILES: OS(=O)(=O)CCCN1CCOCC1
LogP: -2.94 at · -2.94 at 20℃
EPA: 4 · 4-Morpholinepropanesulfonic acid (1132-61-2)
Absorption: 0.05 at · ≤0.05 at 260nm≤0.05 at 280nm

화학적 성질

White/clear crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 45.9% (189 of 412) of reports.

Warning

H315 (53.4%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (53.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (52.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 412 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 189 of 412 reports by companies.；There are 16 notifications provided by 223 of 412 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 3건

Chemical: 4-Morpholinepropanesulfonic acid

Status: Active Update: 06-12-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21270；Status: Active Update: 09-11-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21115

MOPS: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryMay cause irritation; [Caledon Laboratories MSDS] See N-Ethylmorpholine.

Hazard Classes and CategoriesSkin Irrit. 2 (53.4%)；Eye Irrit. 2 (53.4%)；STOT SE 3 (52.7%)

규제 정보

Regulatory Information · 3건

Chemical: 4-Morpholinepropanesulfonic acid

Status: Active Update: 06-12-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21270；Status: Active Update: 09-11-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21115

MOPS: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 1
tsca: TSCA listed
rtecs: QE9104530
HS 번호: 29349990
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36
기존화학 물질: 2010-3-4223
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

UsesUsed as a biological buffer; [Merck Index] Used as a laboratory reagent; [Caledon Laboratories MSDS]

General Manufacturing Information4-Morpholinepropanesulfonic acid: ACTIVE

응용 분야 · 2건

용도Due to its inert nature, 3-morpholinopropanesulfonic acid (MOPS) is widely used as a buffer in many biochemical studies. MOPS has been used as a cell culture additive component in lentiviral particle production, a buffering agent in microbial growth medium and nuclei extraction buffer, a component of Roswell Park Memorial Institute (RPMI) medium for diluting fungal inoculum, and a buffer in capillary-zone electrophoresis to test performance. It is also used for the dilution of proteins from algal samples.

일반 설명3-(N-Morpholino)propane sulfonic acid (MOPS) is an N-substituted amino sulfonic acid with a morpholinic ring. MOPS is capable of buffering within a pH range of 6.5-7.9. MOPS is widely used in biological and biochemical studies due to its inert properties. It does not interact with any metal ions in solutions and has significant metal-buffer stability especially with copper (Cu), nickel (Ni), manganese (Mn), zinc (Zn), cobalt (Co) ions. MOPS buffer maintains the pH of the mammalian cell culture medium. MOPS functions to maintain pH in denaturing gel electrophoresis of RNA. MOPS can modify lipid interactions and influence the thickness and barrier properties of membranes. MOPS interacts with bovine serum albumin and stabilizes the protein. Hydrogen peroxide oxidizes MOPS slowly to N-oxide form.

상·하류 제품 정보

상류 원료

프로페인 설톤

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

武汉德晟生化科技有限公司0711-3702650 18971041571 · [email protected]

추가 설명 · 1건

정의ChEBI: 3-(N-morpholino)propanesulfonic acid is a Good's buffer substance, pKa = 7.2 at 20 ℃. It is a member of morpholines, a MOPS and an organosulfonic acid. It is a conjugate acid of a 3-(N-morpholino)propanesulfonate. It is a tautomer of a 3-(N-morpholiniumyl)propanesulfonate.