Magnesium Acetate (HCID 8896)

개요

Magnesium acetate is the magnesium salt of acetic acid. It is functionally related to an acetic acid.

이름 및 식별자

우선 이름: Magnesium Acetate
IUPAC: magnesium diacetate
현지명: 마그네슘 아세트산
영어명: Magnesium acetate
분자식: C4H6MgO4
분자량: 142.39

이름 및 동의어

Magnesium acetate142-72-3Magnesium diacetateACETIC ACID, MAGNESIUM SALTMagnesium di(acetate)Mg AcetateAcetic acid magnesium saltMagnesium acetate anhydrousAcetic acid, magnesium salt (2:1)Mg(II) acetateMagnesium acetate, mg(oac)2DTXSID7027097

이름 더 보기

마그네슘아세트산아세트산,마그네슘염삭산마그네슘마그네슘아세트산마그네슘아세테이트Nu-MagC4H6MgO4Cromosan*MagnesiumAcetateBpacetatedemagnesiummagnesiumdiacetate

NSC-757980E95JZY48KDTXCID207097CHEBI:62964NSC75798RefChem:800477205-554-9Cromosan

데이터베이스 식별자

CAS: 142-72-3
PubChem CID: 8896
DTXSID: DTXSID7027097
ChEMBL: CHEMBL1200691
ChEBI: CHEBI:62964
UNII: 0E95JZY48K
EC Number: 205-554-9
Nikkaji: J43.168K

물성

구조 계산 물성

극성 표면적: 80.3 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 4
회전 가능 결합 수: 0
무거운 원자 수: 9
형식 전하: 0
복잡도: 25.5

실험 및 물리화학적 성질

Chemical ClassesMetals -> Organic Acids, Metal Salts

Cosmetics · 2건

Cosmetic ingredients (Magnesium Acetate) -> CIR (Cosmetic Ingredient Review)

Buffering

Human Drugs · 2건

FDA approved drugs -> Active ingredient

Physical Description · 2건

Liquid; Large Crystals

Tetrahydrate: Colorless or white deliquescent solid; [Merck Index] White hygroscopic crystals with a mild odor of acetic acid; [Mallinckrodt Baker MSDS]

물리화학적 성질

녹는점: 72 · 72-75 °C(lit.)
밀도: 1.5 · 1.5000
굴절률: 20 · n20/D 1.358
용해도: 2 O: · H2O: 1 M at 20 °C, 투명, 무색
물리적 상태: 액체
산도 계수 (pKa): 4.756 · 4.756[at 20 ℃]
색상: white orthorhombic/monoclinic crystals, crystalline
수소이온지수(pH): 7.95 · 7.95(1 mM solution);8.23(10 mM solution);8.41(100 mM solution);8.78(1000 mM solution)
수용성: 물과 섞이거나 혼합하기 어렵지 않습니다.
Merck: 13 · 13,5676
BRN: 3692530 · 3692530
안정성: 안정적인. 강한 산화제와 호환되지 않습니다. 습기를 피하십시오.
화장품 원료 기능: 버퍼링
InChI: 1S/2C2H4O2.Mg/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
InChIKey: UEGPKNKPLBYCNK-UHFFFAOYSA-L
SMILES: CC(=O)O[Mg]OC(C)=O
LogP: -1.38 · -1.38
NIST: Magnesium acetate(142-72-3)
EPA: Magnesium acetate (142-72-3)

화학적 성질

white deliquescent crystals

안전 및 규제

GHS 분류

GHS Classification · 3건

This chemical does not meet GHS hazard criteria for 99.5% (2416 of 2427) of all reports.

Not Classified

Aggregated GHS information provided per 2427 reports by companies from 3 notifications to the ECHA C&L Inventory.

유해성 정보

Regulatory Information · 4건

Chemical: Acetic acid, magnesium salt

Acetic acid, magnesium salt (2:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, magnesium salt (2:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 10-10-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13613

Acetic acid, magnesium salt: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Acetic acid, magnesium salt: Human health tier I assessment

Hazards Summary · 1건

Members of the acetic acid and salts subcategory demonstrate low acute oral, dermal, and inhalation toxicity; Hyperplasia of the esophagus and forestomach in repeated-dose oral studies of rats; Increased spleen and kidney weights and signs of kidney injury in continuous inhalation studies at 23-31 ppm/day (60-80 mg/m3/day); No maternal or developmental toxicity in mice, rats, or rabbits in oral studies (doses up to 1,600 mg/kg/day); No evidence of mutagenicity; [EPA ChAMP: Hazard Characterization] May cause irritation; [Mallinckrodt Baker MSDS] See Sodium acetate.

EPA Safer ChemicalChemical: Magnesium acetate

Hazard Classes and CategoriesNot Classified

안전 및 보호

Protective Action Criteria (PAC) · 3건

26 [mg/m3]

280 [mg/m3]

1700 [mg/m3]

독성 정보

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: AI5600000
safety_code: 22-24/25
기존화학 물질: KE-22674
F 고인화성물질: 3
스토리지 클래스: 10 - Combustible liquids

화학 및 산업

용도 및 제조

Uses · 2건

CIR ingredient: Magnesium Acetate

Used as a buffer and to detect sodium; [Merck Index] Used as a catalyst for sulfuric acid; [EPA OHM/TADS] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

U.S. Production2023: 10,000,000 - <50,000,000 lb

Consumer UsesOther

Industry UsesDye

Use Classification · 4건

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food Additives -> FOOD_ADDITIVE -> JECFA Functional Classes

Cosmetics -> Buffering

General Manufacturing Information · 2건

All Other Basic Inorganic Chemical Manufacturing

Acetic acid, magnesium salt (2:1): ACTIVE

응용 분야 · 2건

개요Anhydrous Magnesium Acetate has the chemical formula Mg(CH3COO)2 and in its hydrous form, Magnesium Acetate Tetrahydrate, it has the chemical formula Mg(CH3COO)2.4H2O. In this compound the magnesium metal has an oxidation state of 2+. Magnesium acetate is the magnesium salt of acetic acid.It is deliquescent and upon heating, it decomposes to form magnesium oxide.Magnesium acetate is commonly used as a source of magnesium or as a chemical reagent.

용도Dye fixative in textile printing, deodorant, disinfectant, and antiseptic. Magnesium acetate is used in chemistry and molecular biology as a reagent and a source of magnesium. Magnesium has a variety of biological roles in enzymology, cell membrane and wall structural integrity, muscle cell physiology, and nucleic acid structure.Magnesium is an essential co-factor in many enzymes, including deoxyribonuclease (DNase), the restriction enzymes EcoR I and EcoR V, and Ribonuclease H. Magnesium also stabilizes polymeric nucleic acids such as transfer RNA and ribozymes. Magnesium acetate has been widely used in the crystallization of proteins. A protocol for the separation of MB and BB isoenzymes of creatine kinase and the LD1 isoenzyme of lactate dehydrogenase that involves elution with magnesium acetate has been published.