2-Amino-5-chlorophenol (HCID 91591)

이름 및 식별자

우선 이름: 2-Amino-5-chlorophenol
IUPAC: 2-amino-5-chlorophenol
영어명: 2-Amino-5-chlorophenol
분자식: C6H6ClNO
분자량: 143.57

이름 및 동의어

2-Amino-5-chlorophenol28443-50-74-chloro-2-hydroxyanilinePhenol, 2-amino-5-chloro-5-chloro-2-aminophenol6VK2H53LQNDTXSID6067385CHEBI:75051RefChem:85263DTXCID0037819249-020-3MFCD02093863

이름 더 보기

TIMTEC-BB SBB0041372-Amino-5-chlorophenCyclohexane Impurity 1Lenvatinib Impurity 82Chlorzoxazone Impurity 242-Amino-5-chlorophenol 97%2-Amino-5-chlorophenol,99%

2-amino-5-chloro-phenolEINECS 249-020-35-chloro-o-aminophenol2-hydroxy-4-chloroanilineUNII-6VK2H53LQNEC 249-020-3SCHEMBL1033293-CHLORO-6-AMINOPHENOL

데이터베이스 식별자

CAS: 28443-50-7
PubChem CID: 91591
DTXSID: DTXSID6067385
ChEBI: CHEBI:75051
UNII: 6VK2H53LQN
EC Number: 249-020-3
Nikkaji: J88.559B

물성

구조 계산 물성

XLogP: 1.8
극성 표면적: 46.3 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 9
형식 전하: 0
복잡도: 99

물리화학적 성질

녹는점: 145 · 145-153 °C (lit.)
끓는 점: 185.5 °C · 185.5°C (rough estimate)
밀도: 1.2028 · 1.2028 (rough estimate)
증기압: 0.002 · 0.002-0.094Pa at 20-50℃
굴절률: 1.5618 · 1.5618 (estimate)
저장 조건: -20 °C, · -20°C, stored under nitrogen
용해도: 메탄올에 용해됨
산도 계수 (pKa): 8.79 · 8.79±0.10(Predicted)
물리적 상태: 가루
색상: 연한 갈색
InChI: InChI=1S/C6H6ClNO/c7-4-1-2-5(8)6(9)3-4/h1-3,9H,8H2
InChIKey: FZCQMIRJCGWWCL-UHFFFAOYSA-N
SMILES: C1(O)=CC(Cl)=CC=C1N
EPA: 2 · Phenol, 2-amino-5-chloro- (28443-50-7)

화학적 성질

light brown fine crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (97.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (95.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 43 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory InformationStatus: Cease Manufacture Update: 19-02-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/12346

Hazard Classes and CategoriesSkin Irrit. 2 (97.7%)；Eye Irrit. 2 (97.7%)；STOT SE 3 (95.3%)

규제 정보

Regulatory InformationStatus: Cease Manufacture Update: 19-02-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/12346

안전 데이터

wgk: 3
tsca: TSCA listed
HS 번호: 29222990
risk_code: 36/37/38-20/21/22
hazard_code: Xi,Xn
safety_code: 26-36-36/37/39
위험 등급: 6.1
위험 참고 사항: Irritant
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

General Manufacturing InformationPhenol, 2-amino-5-chloro-: ACTIVE

응용 분야 · 2건

용도2-Amino-5-chlorophenol may be used to synthesize 2-amino-5-chloromuconic semialdehyde and benzoxazole derivatives.

일반 설명2-Amino-5-chlorophenol can be synthesized from 2-chloro-5-nitrophenol via reduction. It can also be obtained from 1-chloro-4-nitrobenzene by using a bacterial strain LW1. 2-Amino-5-chlorophenol participates in the condensation reaction with acetylferrocene to afford ferrocenyl Schiff bases bearing a phenol group.

상·하류 제품 정보

하류 제품

공급사50 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海达立康医药科技有限公司18658316824

温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]

环生美森医药技术（山东）有限公司0531-88762217 18301471076 · [email protected]

추가 설명

정의ChEBI: Phenol carrying amino and chloro substituents at positions 2 and 5 respectively. It is part of the degradation pathway of 4-chloronitrobenzene, CHEBI:34399.