Hydrochloric Acid → N-[2-[(Aminothioxomethyl)hydrazono]-2-phenylethyl]acetamide
반응식
[NH2:1][NH:2][C:3]([NH2:5])=[S:4].O=[C:7]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH2:8][NH:9][C:10](=[O:12])[CH3:11].Cl.O>CO>[NH2:5][C:3]([NH:2][N:1]=[C:7]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH2:8][NH:9][C:10](=[O:12])[CH3:11])=[S:4]참가 물질
6
실험 절차
Thiosemicarbazide (1.98 g, 20 mmol) was added to a solution of N-(2-oxo-2-phenyl-ethyl)-acetamide (3.84 g, 20 mmol, prepared in the previous step, in 70 ml of methanol plus 5.4 ml of 1N HCl plus 5.0 ml of water and the reaction stirred at room temperature overnight. The solid formed was collected by filtration and dried to give 3.9 g (78%) of the title compound as a white solid, mp 208-211° C.
후처리
- customThe solid formed
- filtrationwas collected by filtration
- customdried
출처 및 근거
- ORD 기록
- ord-d3dc8dc7680d4ea2acf7c93c70220ce4
- 출처 데이터셋
- uspto-grants-2000_04
- 특허 번호
- US06049006
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