Acetaldehyde → 2-chloroethanal O-[2-(morpholin-4-yl)ethyl]oxime

HRID 10171

반응식

HRID 10171 반응식
[CH:1](=O)[CH3:2].[ClH:4].Cl.[N:6]1([CH2:12][CH2:13][O:14][NH2:15])[CH2:11][CH2:10][O:9][CH2:8][CH2:7]1.[OH-].[Na+]>O>[N:6]1([CH2:12][CH2:13][O:14][N:15]=[CH:2][CH2:1][Cl:4])[CH2:11][CH2:10][O:9][CH2:8][CH2:7]1

참가 물질

5

반응물 3

HCID 177AcetaldehydeHCID 14798Sodium Hydroxide2회HCID 21978765HCID 21978765, 화합물

생성물 1

HCID 738572932-chloroethanal O-[2-(morpholin-4-yl)ethyl]oxime수율 100%

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

A mixture of acetaldehyde (0.1 mL of a 50 wt % soln. in water), O-[2-((morpholin-4-yl))ethyl]hydroxylamine dihydrochloride (0.14 g), NaOH (2N, 0.64 mL) and water (5 mL) was stirred at room temperature overnight. The solution was made basic with NaOH (1N) and extracted with dichloromethane. The organic layer was dried (Na2SO4), and concentrated in vacuo to afford 2-chloroethanal O-[2-((morpholin-4-yl))ethyl]oxime (0.13 g, ˜100%), which was used as such.

후처리

  1. extractionextracted with dichloromethane
  2. dry with materialThe organic layer was dried (Na2SO4)
  3. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-43d79bad5eef413a95504b9e5c6de2be
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07094779B2

연결된 노트

불러오는 중…