Pyridine → Acetamide, N-(3,5-dichlorophenyl)-
반응식
N1C=CC=CC=1.[Cl:7][C:8]1[CH:9]=[C:10]([NH2:15])[CH:11]=[C:12]([Cl:14])[CH:13]=1.[C:16](OC(=O)C)(=[O:18])[CH3:17]>C(Cl)(Cl)Cl>[Cl:7][C:8]1[CH:9]=[C:10]([NH:15][C:16](=[O:18])[CH3:17])[CH:11]=[C:12]([Cl:14])[CH:13]=1참가 물질
5
실험 절차
200 ml of pyridine are added dropwise to 100 g of 3,5-dichlorophenylamine in 3000 ml of chloroform, followed by addition of 90 ml of acetic anhydride. The reaction mixture is stirred for 12 hours at room temperature. The solvents are evaporated off under reduced pressure and the residue obtained is recrystallized from 1000 ml of ethyl acetate; m.p.=182° C.
후처리
- customThe solvents are evaporated off under reduced pressure
- customthe residue obtained
- customis recrystallized from 1000 ml of ethyl acetate
출처 및 근거
- ORD 기록
- ord-8aaa631de4e64c6eab26d209db2f0332
- 출처 데이터셋
- uspto-grants-2002_11
- 특허 번호
- US06482986B1
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