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Hydrochloric Acid → HCID 15670949, 화합물

HRID 1031642
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HRID 1031642 반응식
[C:1]([C:3](=[C:9]([C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)[C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=1)[CH2:4][CH2:5][C:6]([OH:8])=[O:7])#[N:2].[OH-:26].[Na+].Cl>C(O)CO>[C:1]([C:3](=[C:9]([C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=1)[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)[CH2:4][CH2:5][C:6]([OH:8])=[O:7])(=[O:26])[NH2:2]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 65913Satigrel

생성물 1

HCID 15670949HCID 15670949, 화합물

시약·촉매·용매 1

HCID 174Ethylene Glycol용매

실험 절차

Two grams of the acid obtained in Example 4 was heated with 10 ml of a 5N aqueous solution of NaOH in 50 ml of ethylene glycol at 150° C. for 12 hours. The product mixture was acidified with hydrochloric acid and extracted with ethyl acetate. The extract was treated with the chromatography of silicagel to obtain 0.5 g of the above intended compound.

후처리

  1. extractionextracted with ethyl acetate
  2. additionThe extract was treated with the chromatography of silicagel

출처 및 근거

ORD 기록
ord-09d4811ce8e446eebcf462eee75c629a
출처 데이터셋
uspto-grants-1990_09
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04954523

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