Propanal → 1-(1-Propenyl)-2-nitroiminoimidazolidine

HRID 1033547노트

반응식

HRID 1033547 반응식
[N+:1]([N:4]=[C:5]1[NH:9][CH2:8][CH2:7][NH:6]1)([O-:3])=[O:2].P(Cl)(Cl)(Cl)=O.[CH:15](=O)[CH2:16][CH3:17]>O>[CH:15]([N:6]1[CH2:7][CH2:8][NH:9][C:5]1=[N:4][N+:1]([O-:3])=[O:2])=[CH:16][CH3:17]

참가 물질

5

반응물 3

HCID 527PropanalHCID 24813Phosphorus oxychlorideHCID 135413413N-nitroimidazolidin-2-imine

생성물 1

HCID 1363783921-(1-Propenyl)-2-nitroiminoimidazolidine수율 32.5%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture comprising 4.0 g of 2-nitroiminoimidazolidine, 20 ml of 1,3-dimethyl-2imidazolidine, 7.5 g of phosphorus oxychloride and 2.7 g of propionaldehyde was stirred for 30 minutes at room temperature. The reaction mixture was poured into water, extracted with ethyl acetate, washed with water, dried (with anhydrous MgSO4) and concentrated. The crystals thus precipitated out were sludged with ethyl acetate, filtrated and dried to give 1.7 g of 1-(1-propenyl)-2-nitroiminoimidazolidine.

후처리

  1. extractionextracted with ethyl acetate
  2. washwashed with water
  3. dry with materialdried (with anhydrous MgSO4)
  4. concentrationconcentrated
  5. customThe crystals thus precipitated out
  6. filtrationfiltrated
  7. customdried

출처 및 근거

ORD 기록
ord-98bc24d177894b46877e9ca5b36e629b
출처 데이터셋
uspto-grants-1994_05
특허 번호
US05310920

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