Citric Acid → 5-(3,3-dimethyl-but-1-ynyl)-3-[((1R)-4-methyl-cyclohex-3-enecarbonyl)-(1-oxa-spiro[2.5]oct-6-yl)-amino]thiophene-2-carboxylic acid methyl ester

반응식

[Cl-].[CH3:2][S+](C)(C)=O.[H-].[Na+].[CH3:9][O:10][C:11]([C:13]1[S:14][C:15]([C:35]#[C:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[CH:16][C:17]=1[N:18]([C:26]([C@@H:28]1[CH2:33][CH2:32][C:31]([CH3:34])=[CH:30][CH2:29]1)=[O:27])[CH:19]1[CH2:24][CH2:23][C:22](=[O:25])[CH2:21][CH2:20]1)=[O:12].C(O)(=O)CC(CC(O)=O)(C(O)=O)O>CS(C)=O.C1COCC1>[CH3:9][O:10][C:11]([C:13]1[S:14][C:15]([C:35]#[C:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[CH:16][C:17]=1[N:18]([C:26]([C@@H:28]1[CH2:33][CH2:32][C:31]([CH3:34])=[CH:30][CH2:29]1)=[O:27])[CH:19]1[CH2:20][CH2:21][C:22]2([O:25][CH2:2]2)[CH2:23][CH2:24]1)=[O:12]