Hydrochloric Acid → Benzenesulfonyl azide

HRID 1066680

반응식

HRID 1066680 반응식
[C:1]1([S:7]([NH:10][NH2:11])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.C(O)(=O)CCCCCCCCCCCCCCCCC.[NH2:33]CCS(O)(=O)=O.N([O-])=O.[Na+].N([O-])=O>O>[C:1]1([S:7]([N:10]=[N+:11]=[N-:33])(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

8

반응물 6

HCID 313Hydrochloric AcidHCID 946NitriteHCID 1123TaurineHCID 5281Stearic AcidHCID 65723Benzenesulfonyl hydrazideHCID 23668193Sodium Nitrite2회

생성물 1

HCID 555606Benzenesulfonyl azide

시약·촉매·용매 1

HCID 962Water용매

실험 절차

25 g of benzenesulfonic acid hydrazide, 200 ml of water, 20 ml of 10 N hydrochloric acid, and 1.25 g of a condensation product of stearic acid with taurine were stirred for 30 minutes. After 60 g of ice were added, 34 ml of an aqueous sodium nitrite solution having a content of 30 g of sodium nitrite per 100 ml of solution were added dropwise over a period of about 30 minutes. The mixture was stirred for 30 minutes while an excess of nitrite was maintained. The excess nitrite was destroyed with a small amount of amidosulfonic acid and the mixture was neutralized with about 5 ml of 10 N sodium hydroxide solution. An emulsion of benzenesulfonic acid azide was obtained.

후처리

  1. additionwere added dropwise over a period of about 30 minutes
  2. temperaturewas maintained
  3. customThe excess nitrite was destroyed with a small amount of amidosulfonic acid

출처 및 근거

ORD 기록
ord-17aabdd75a404e64b68e8edb000d9ee6
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06245138B1

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