Hydrochloric Acid → HCID 21193379, 화합물

HRID 1068410노트

반응식

HRID 1068410 반응식
C[O:2][C:3](=[O:38])[CH:4]([C:14]1[N:15]=[CH:16][N:17]([C:19]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:18]=1)[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]#[N:13])=[CH:8][CH:7]=1.[OH-].[Li+].Cl>C1COCC1>[C:32]1([C:19]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)([C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=2)[N:17]2[CH:18]=[C:14]([CH:4]([CH2:5][C:6]3[CH:11]=[CH:10][C:9]([C:12]#[N:13])=[CH:8][CH:7]=3)[C:3]([OH:38])=[O:2])[N:15]=[CH:16]2)[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 54160280HCID 54160280, 화합물

생성물 1

HCID 21193379HCID 21193379, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A solution of the 2-{1-(triphenylmethyl)-1H-imidazol-4-yl}-2-(4-cyanobenzyl)-acetic acid methyl ester in THF was treated with 1 equivalent of 1M lithium hydroxide solution. Upon consumption of starting material as determined by t.l.c, 1 equivalent of hydrochloric acid was added and the solution evaporated to dryness in vacuo. The material obtained in this manner could be used without further purification.

후처리

  1. customUpon consumption of starting material
  2. additionwas added
  3. customthe solution evaporated to dryness in vacuo
  4. customThe material obtained in this manner
  5. customcould be used without further purification

출처 및 근거

ORD 기록
ord-5f4c566ec9f74772ae799378adb97b13
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06248756B1

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