Sodium Hydroxide → 2-(Pyrimidin-2-yloxy)acetic acid
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[O:7][CH2:8][C:9]([O:11]CC)=[O:10].[OH-].[Na+]>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[O:7][CH2:8][C:9]([OH:11])=[O:10]참가 물질
4
실험 절차
Ethyl 2-pyrimidinyloxyacetate (1.4 g) was dissolved in ethanol (10 ml). Sodium hydroxide (2M aq) was added and the mixture was stirred for 64 h. The solvent was evaporated and the residue was dissolved in water, filtered and the acidified with concentrated hydrochloric acid. The resulting precipitate was collected and dried to give the subtitle compound (0.698 g).
후처리
- customThe solvent was evaporated
- dissolutionthe residue was dissolved in water
- filtrationfiltered
- customThe resulting precipitate was collected
- customdried
출처 및 근거
- ORD 기록
- ord-fde72d6116224d3081aa845e2d8ee2c7
- 출처 데이터셋
- uspto-grants-2005_06
- 특허 번호
- US06903085B1
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