Hydrochloric Acid → 125960-58-9
반응식
FC(F)(F)C([NH:5][CH2:6][CH2:7][C:8]1[CH:9]=[CH:10][C:11]([O:18][CH3:19])=[C:12]([S:14]([NH2:17])(=[O:16])=[O:15])[CH:13]=1)=O.[OH-].[Na+].[ClH:24]>CO>[ClH:24].[NH2:5][CH2:6][CH2:7][C:8]1[CH:9]=[CH:10][C:11]([O:18][CH3:19])=[C:12]([S:14]([NH2:17])(=[O:16])=[O:15])[CH:13]=1참가 물질
5
실험 절차
To a suspension of 10.0 g of 5-[2-(trifluoroacetylamino)ethyl]-2-methoxybenzenesulfonamide in 100 ml of methanol were added 60 ml of 10% sodium hydroxide aqueous solution with stirring at room temperature and the reaction mixture was stirred for 30 minutes. The reaction mixture was acidfied with 13 ml of hydrochloric acid. The precipitate was filtered and recrystallized from water to give 4.22 g of the desired compound as colorless needles, m.p. 263°-266° C.
후처리
- stirringthe reaction mixture was stirred for 30 minutes
- filtrationThe precipitate was filtered
- customrecrystallized from water
출처 및 근거
- ORD 기록
- ord-35e5f50572eb4355a73dfd2f0697db81
- 출처 데이터셋
- uspto-grants-1990_11
- 특허 번호
- US04971990
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