Trifluoroacetic acid → 3-Formyl-2,4,6-trimethylbenzenesulfonyl fluoride

HRID 1086656

반응식

HRID 1086656 반응식
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH3:9])[CH:3]=1.[F:10][S:11]([OH:14])(=O)=[O:12].[C]=O.FC(F)(F)[C:19](O)=[O:20]>[Sb](F)(F)(F)(F)F>[CH:19]([C:3]1[C:2]([CH3:1])=[C:7]([S:11]([F:10])(=[O:14])=[O:12])[C:6]([CH3:8])=[CH:5][C:4]=1[CH3:9])=[O:20]

참가 물질

6

반응물 4

HCID 6422Trifluoroacetic acidHCID 7947Mesitylene2회HCID 24603Fluorosulfuric acid2회HCID 178418416HCID 178418416, 화합물

생성물 1

HCID 117760063-Formyl-2,4,6-trimethylbenzenesulfonyl fluoride수율 30%

시약·촉매·용매 1

HCID 24557Antimony pentafluoride용매2회

실험 절차

18.9 ml of 1,3,5-trimethylbenzene was reacted with 20 ml of fluorosulfonic acid and carbon monoxide in the presence of 10 ml of antimony pentafluoride and 10 ml of trifluoroacetic acid as a solvent at 20° C. for 48 hours in substantially the same manner as that of Example 1. The molar ratio of 1,3,5-trimethylbenzene : fluorosulfonic acid : antimony pentafluoride was 1 : 3.5 : 1.4, while the consumption of carbon monoxide was 2.24 λ. The same analyses as those of Example 1 were made to confirm the formation of 6.9 g of 3-formyl-2,4,6-trimethylbenzenesulfonyl fluoride (compound No. 7) in a yield of 30 % based on 1,3,5-trimethylbenzene. mass spectrum: M+ (m/e)=230.

후처리

  1. customwhile the consumption of carbon monoxide

출처 및 근거

ORD 기록
ord-d3735b04fd1241c5b40e775bd602b0f6
출처 데이터셋
uspto-grants-1991_07
특허 번호
US05030752

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