Hydrogen Peroxide → 2-Propylpyridine 1-oxide

HRID 1091053

반응식

HRID 1091053 반응식
[CH2:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)[CH2:2][CH3:3].[OH:10]O.[OH-].[Na+]>C(O)(=O)C>[CH2:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N+:5]=1[O-:10])[CH2:2][CH3:3]

참가 물질

5

반응물 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 693202-Propylpyridine

생성물 1

HCID 886162-Propylpyridine 1-oxide

시약·촉매·용매 1

HCID 176Acetic Acid용매2회

반응 조건

온도
65 °C

실험 절차

20 ml of 2-n-propylpyridine were dissolved in 60 ml of glacial acetic acid, mixed with 40 ml of H2O2 (30%) and stirred for 16 hours at room temperature and 3 hours at 65° C. The acetic acid was then partly rotated out, the residue was adjusted to pH 8 with NaOH (20%), extracted with dichloromethane and the organic phase rotated in to dryness. 20 g of crude 2-propylpyridine-N-oxide were obtained.

후처리

  1. extractionextracted with dichloromethane

출처 및 근거

ORD 기록
ord-587afd339fd440a496b89d5fef38a299
출처 데이터셋
uspto-grants-1992_01
특허 번호
US05084458

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