Water → HCID 57599729, 화합물

HRID 1091522노트

반응식

HRID 1091522 반응식
[NH2:1][C:2]1[C:9]([O:10][CH3:11])=[C:8]([O:12][CH2:13][O:14][CH3:15])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=S.O.[CH2:31](N)[CH2:32][NH2:33]>>[NH:5]1[CH2:31][CH2:32][N:33]=[C:4]1[C:3]1[C:2]([NH2:1])=[C:9]([O:10][CH3:11])[C:8]([O:12][CH2:13][O:14][CH3:15])=[CH:7][CH:6]=1

참가 물질

5

반응물 4

HCID 962WaterHCID 3301EthylenediamineHCID 14817Phosphorus sulfide (P2S5)HCID 57599653HCID 57599653, 화합물

생성물 1

HCID 57599729HCID 57599729, 화합물수율 51.1%

실험 절차

A solution of 2-amino-3-methoxy-4-(methoxymethoxy)benzonitrile 475 mg (2.28 mmol) and phosphorus pentasulfide 25.4 mg (0.11 mmol) in ethylenediamine 2.75 g was stirred at 120° C. for overnight. The reaction mixture was cooled to room temperature and poured into water. The precipitate was collected and washed with water to give the title compound 293 mg as white solid. Yield 51.1%.

후처리

  1. customThe precipitate was collected
  2. washwashed with water

출처 및 근거

ORD 기록
ord-d9e349da703a456b8a0bd0657ab107da
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08129386B2

반응 노트

불러오는 중…