Hydrochloric Acid → HCID 178524187, 화합물

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[OH-].[Na+].[CH:3]1([N:6]2[C:14]3[C:9](=[C:10]([C:20]4[NH:24][N:23]=[N:22][N:21]=4)[CH:11]=[C:12]([C:15]([O:17]CC)=[O:16])[CH:13]=3)[CH:8]=[CH:7]2)[CH2:5][CH2:4]1.Cl>CO>[CH:3]1([N:6]2[C:14]3[C:9](=[C:10]([C:20]4[NH:24][N:23]=[N:22][N:21]=4)[CH:11]=[C:12]([C:15]([OH:17])=[O:16])[CH:13]=3)[CH:8]=[CH:7]2)[CH2:4][CH2:5]1

참가 물질

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온도: 60 °C

실험 절차

In a 500-mL egg plant-type flask, aqueous 5 N sodium hydroxide solution (11 mL, 55 mmol) was added to an MeOH solution (70 mL) of ethyl 1-cyclopropyl-4-(tetrazol-5-yl)-1H-indole-6-carboxylate (5.40 g), and stirred at 60° C. for 8 hours. The reaction solution was left cooled, aqueous 5 N hydrochloric acid solution (12 mL) was added thereto, and the formed precipitate was taken out through filtration. This was washed with water and dried under reduced pressure to obtain the title compound as a colorless solid.