Hydrochloric Acid → HCID 3041523, 화합물

반응식

Cl.Cl.[NH2:3][C:4]1[C:9]([C:10]([F:13])([F:12])[F:11])=[CH:8][C:7]([C:14](=[O:21])[CH2:15][NH:16][CH:17]2[CH2:20][CH2:19][CH2:18]2)=[CH:6][C:5]=1[Cl:22].[BH4-].[Na+]>>[NH2:3][C:4]1[C:9]([C:10]([F:11])([F:12])[F:13])=[CH:8][C:7]([CH:14]([OH:21])[CH2:15][NH:16][CH:17]2[CH2:18][CH2:19][CH2:20]2)=[CH:6][C:5]=1[Cl:22]

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 4311764Sodium borohydride

HCID 22765889HCID 22765889, 화합물

생성물 1

HCID 3041523HCID 3041523, 화합물

실험 절차

m.p. of the hydrochloride: 177°-178° C., was prepared from 4'-amino-3'-chloro-2-cyclobutylamino-5'-trifluoromethyl-acetophenone hydrochloride and sodium borohydride analogous to Example 1.

출처 및 근거

ORD 기록: ord-18accaf239bb447b8a72268462b04e41
출처 데이터셋: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04119710

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