Methyl iodide → 3-Methylmercapto-4-n-butyl-1,2,4-triazole
반응식
I[CH3:2].[SH:3][C:4]1[N:8]([CH2:9][CH2:10][CH2:11][CH3:12])[CH:7]=[N:6][N:5]=1.[OH-].[Na+]>CO>[CH3:2][S:3][C:4]1[N:8]([CH2:9][CH2:10][CH2:11][CH3:12])[CH:7]=[N:6][N:5]=1참가 물질
5
실험 절차
Iodomethane (9.05 g. or 0.0637 mole) was added to a solution of 10 g. of 3-mercapto-4-n-butyl-1,2,4-triazole, methanol (100 ml.), and sodium hydroxide (2.55 g. or 0.0637 mole). This solution was then refluxed for 2 hours. The solvent was then removed in vacuum and the residue was dissolved in benzene. This solution was washed with water, dried and the benzene removed in vacuum. The residual oil was distilled to give 3-methylmercapto-4-n-butyl-1,2,4-triazole, b.p. 128°-131° C./ 2 mm. The structure was confirmed by its nuclear magnetic resonance spectrum.
후처리
- temperatureThis solution was then refluxed for 2 hours
- customThe solvent was then removed in vacuum
- dissolutionthe residue was dissolved in benzene
- washThis solution was washed with water
- customdried
- customthe benzene removed in vacuum
- distillationThe residual oil was distilled
출처 및 근거
- ORD 기록
- ord-5e282fa862044fe388add7e410aefa20
- 출처 데이터셋
- uspto-grants-1978_10
- 특허 번호
- US04120864
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