Tetrahydrofuran → N-[5-(bromomethyl)pyrazin-2-yl]-2-(3-chloro-4-methylsulfonylphenyl)-3-cyclopentylpropanamide

HRID 1112976노트

반응식

[C:49]([Br:50])([Br:51])([Br:52])[Br:53].[Cl:1][c:2]1[cH:3][c:4]([CH:12]([C:13](=[O:14])[NH:15][c:16]2[n:17][cH:18][c:19]([CH2:22][OH:23])[n:20][cH:21]2)[CH2:24][CH:25]2[CH2:26][CH2:27][CH2:28][CH2:29]2)[cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[CH3:11].[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1.[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[Cl:1][c:2]1[cH:3][c:4]([CH:12]([C:13](=[O:14])[NH:15][c:16]2[n:17][cH:18][c:19]([CH2:22][Br:50])[n:20][cH:21]2)[CH2:24][CH:25]2[CH2:26][CH2:27][CH2:28][CH2:29]2)[cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[CH3:11]