Methyl iodide → HCID 20513435, 화합물

반응식

[H-].[Na+].[C:3]([CH:5]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH3:24])[C:12]=1[O:25][CH3:26])[C:6]([O:8][CH2:9][CH3:10])=[O:7])#[N:4].[CH3:27]I>>[C:3]([C:5]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH3:24])[C:12]=1[O:25][CH3:26])([CH3:27])[C:6]([O:8][CH2:9][CH3:10])=[O:7])#[N:4]

참가 물질

반응물 3

HCID 6328Methyl iodide

HCID 24758Sodium hydride

HCID 20513460HCID 20513460, 화합물

생성물 1

HCID 20513435HCID 20513435, 화합물수율 94.3%

실험 절차

Sodium hydride (50%, 1 g), ethyl 2-cyano-2-[2-methoxy-3-(o-tolyloxy)phenyl]acetate (6.2 g) and methyl iodide (4.1 g) were treated in a similar manner to that of Example 10-(5) to give oily ethyl 2-cyano-2-[2-methoxy-3-(o-tolyloxy)phenyl]propionate (6.1 g).

출처 및 근거

ORD 기록: ord-be0dc4fd7bc7416b8abfd5ab312451b2
출처 데이터셋: uspto-grants-1983_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04367238

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