Benzene, 1-fluoro-2-methyl-4-nitro- → HCID 61151226, 화합물

HRID 1172617

반응식

HRID 1172617 반응식
C([O:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)C.[N+:12]([C:15]1[CH:16]=[CH:17][C:18](F)=[C:19]([CH3:21])[CH:20]=1)([O-:14])=[O:13].C(N(CC)C(C)C)(C)C>CS(C)=O>[OH:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][N:9]([C:18]2[CH:17]=[CH:16][C:15]([N+:12]([O-:14])=[O:13])=[CH:20][C:19]=2[CH3:21])[CH2:10][CH2:11]1

참가 물질

5

반응물 3

HCID 68001Benzene, 1-fluoro-2-methyl-4-nitro-HCID 81531DiisopropylethylamineHCID 27346431-(2-Ethoxyethyl)piperazine

생성물 1

HCID 61151226HCID 61151226, 화합물

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

In the same manner as in Production Example 5-1, but using 4-(2-ethoxyethyl)piperazine in place of N-ethylpiperazine used in Production Example 5-1, using 5-nitro-2-fluorotoluene in place of 2-fluoro-5-nitrobenzyl alcohol, using N,N-diisopropylethylamine in place of potassium carbonate, and using dimethylsulfoxide in place of N-methylpyrrolidone, the entitled compound was obtained as a yellow solid.

후처리

  1. customthe entitled compound was obtained as a yellow solid

출처 및 근거

ORD 기록
ord-3a6ce5ec99624181b11a0773d017189c
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07834019B2

연결된 노트

불러오는 중…