Hydrochloric Acid → 6-Azidosulfonylhexyltriethoxysilane

HRID 1194067노트

반응식

HRID 1194067 반응식
[N-:1]=[N+:2]=[N-:3].[Na+].Cl.[N-]=[N+]=[N-].[CH2:9]([O:11][Si:12]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][S:25](Cl)(=[O:27])=[O:26])([O:16][CH2:17][CH3:18])[O:13][CH2:14][CH3:15])[CH3:10]>P([O-])([O-])(O)=O.[Na+].[Na+].C(Cl)Cl>[CH2:9]([O:11][Si:12]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][S:25]([N:1]=[N+:2]=[N-:3])(=[O:27])=[O:26])([O:13][CH2:14][CH3:15])[O:16][CH2:17][CH3:18])[CH3:10]

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 33557Sodium AzideHCID 33558AzideHCID 86742803HCID 86742803, 화합물

생성물 1

HCID 220457406-Azidosulfonylhexyltriethoxysilane

시약·촉매·용매 2

HCID 6344Dichloromethane용매HCID 24203Sodium Phosphate, Dibasic용매

실험 절차

Sodium azide (1.5 equivalent) in 4 ml of sodium hydrogen phosphate and hydrogen chloride buffer (14.4 g or Na2HPO4 to 4.4 mil conc HCl in 1 liter of distilled water) per gram of azide is added dropwise to a stirred 50 percent solution of triethoxysilylhexane sulfonyl chloride in methylene chloride containing 1 percent Aliquat 336. The mixture is stirred at room temperature for thirty minutes after the addition is complete. The layers are separated. The methylene chloride layer is washed with a saturated salt solution, dried over magnesium sulfate and the methylene chloride is evaporated. Ninety percent solids of a light yellow liquid triethoxysilylhexane sulfonyl azide of about 90 percent purity are obtained.

후처리

  1. additionafter the addition
  2. customThe layers are separated
  3. washThe methylene chloride layer is washed with a saturated salt solution
  4. dry with materialdried over magnesium sulfate
  5. customthe methylene chloride is evaporated

출처 및 근거

ORD 기록
ord-9787aeaaecd34093a042e510810e6d2c
출처 데이터셋
uspto-grants-1989_03
특허 번호
US04812519

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