Caprolactam → Laurocapram

HRID 1194070

반응식

HRID 1194070 반응식
[NH:1]1[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]1=[O:8].[CH2:9](Br)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[OH-].[Na+]>[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C1(C)C=CC=CC=1>[CH2:20]([N:1]1[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]1=[O:8])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH3:9].[CH2:2]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

참가 물질

7

반응물 3

HCID 7768CaprolactamHCID 89191-BromododecaneHCID 14798Sodium Hydroxide

생성물 2

HCID 20667Dilauryl Ether수율 0.8%HCID 42981Laurocapram수율 95%

시약·촉매·용매 2

HCID 74236Tetrabutylammonium Bromide촉매HCID 1140Toluene용매

반응 조건

온도
50 °C

실험 절차

A 1l reactor was charged with 57 g (0.5 mole) of azacycloheptane-2-one, 125 g (0.5 mole) of dodecyl bromide, 182 g of toluene, 3.2 g (2 mole %) of crystalline tetrabutylammonium bromide (TBAB) and 60 g (1.5 moles) of flaky sodium hydroxide. This heterogeneous mixture was stirred at 50° C. for 10 hours. The same aftertreatment as in Example 1 was repeated, giving 133.5 g of 1-dodecylazacycloheptane-2-one (yield of 95.0%) and 0.7 g of dodecyl ether (yield of 0.8%)

출처 및 근거

ORD 기록
ord-4d4e65a2ba9144478ce8f37122aded0f
출처 데이터셋
uspto-grants-1989_03
특허 번호
US04812566

연결된 노트

불러오는 중…