Ethanol → Phenacyl thiocyanate

HRID 1195793노트

반응식

HRID 1195793 반응식
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:10])[CH3:9].[S-:11][C:12]#[N:13].[K+].C(O)C>O>[S:11]([CH2:9][C:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1)=[O:10])[C:12]#[N:13]

참가 물질

5

반응물 3

HCID 702EthanolHCID 750602'-BromoacetophenoneHCID 516872Potassium thiocyanate

생성물 1

HCID 219693Phenacyl thiocyanate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

In accordance with the known process (Beilstein, 8, 94), 10.0 g (50 mmol) of o-bromoacetophenone and 4.9 g (50 mmol) of potassium thiocyanate were added to 80 ml of ethyl alcohol, and the resultant mixture was heated at 80° C. for 3 hours and then allowed to stand overnight. Added to the reaction mixture were 50 ml of water. Precipitated crystals were collected by filtration, washed with 50% aqueous ethyl alcohol and then dried, whereby the title compound was obtained as colorless crystals.

후처리

  1. additionAdded to the reaction mixture
  2. customPrecipitated crystals
  3. filtrationwere collected by filtration
  4. washwashed with 50% aqueous ethyl alcohol
  5. customdried

출처 및 근거

ORD 기록
ord-89cd3467c1aa4bdf84dd26db3d3a38a0
출처 데이터셋
uspto-grants-1992_05
특허 번호
US05112841

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