Acetate → Tert-butyl 2-(5-(methoxycarbonyl)thiophen-2-yl)pyrrolidine-1-carboxylate

HRID 120873

반응식

HRID 120873 반응식
[B-:28]([F:29])([F:30])([F:31])[F:32].[Br:18][c:19]1[cH:20][cH:21][c:22]([C:24](=[O:25])[O:26][CH3:27])[s:23]1.[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH2:11][CH2:12]1.[C:33]([P:34]([C:35]([CH3:36])([CH3:37])[CH3:38])[C:39]([CH3:40])([CH3:41])[CH3:42])([CH3:43])([CH3:44])[CH3:45].[CH2:54]1[CH2:55][CH2:56][CH2:57][CH2:58][CH2:59]1.[CH3:48][O:49][C:50]([CH3:51])([CH3:52])[CH3:53].[CH:13]([Li:14])([CH2:15][CH3:16])[CH3:17].[Cl-:60].[Cl-:62].[NH4+:46].[O-:64][C:65]([CH3:66])=[O:67].[O-:68][C:69]([CH3:70])=[O:71].[OH-:47].[Pd+2:63].[Zn+2:61]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH2:11][CH:12]1[c:19]1[cH:20][cH:21][c:22]([C:24](=[O:25])[O:26][CH3:27])[s:23]1

참가 물질

14

반응물 13

HCID 175Acetate2회HCID 223AmmoniumHCID 312Chloride2회HCID 961HydroxideHCID 8078CyclohexaneHCID 15413tert-Butyl methyl etherHCID 26255TetrafluoroborateHCID 32051Zinc(2+)HCID 83681Tris(1,1-dimethylethyl)phosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 605713Methyl 5-bromothiophene-2-carboxylateHCID 643455N-Boc-pyrrolidineHCID 178418400CID 53628100

생성물 1

HCID 66758891Tert-butyl 2-(5-(methoxycarbonyl)thiophen-2-yl)pyrrolidine-1-carboxylate

출처 및 근거

ORD 기록
ord-736f344884f84883a6b8579cca61d020
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

연결된 노트

불러오는 중…