Dimethyl Sulfoxide → Tert-butyl 2-[6-(2,2,2-trifluoro-1-phenylethoxy)pyrazin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

HRID 1213595노트

반응식

[CH3:13][C:14]([CH3:15])([O-:16])[CH3:17].[CH3:41][S:42]([CH3:43])=[O:44].[Cl:19][c:20]1[cH:21][n:22][cH:23][c:24]([N:26]2[CH2:27][CH:28]3[CH:29]([CH2:30]2)[CH2:31][N:32]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:33]3)[n:25]1.[F:1][C:2]([CH:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[OH:10])([F:11])[F:12].[K+:18]>>[F:1][C:2]([CH:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[O:10][c:20]1[cH:21][n:22][cH:23][c:24]([N:26]2[CH2:27][CH:28]3[CH:29]([CH2:30]2)[CH2:31][N:32]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:33]3)[n:25]1)([F:11])[F:12]