2,3-Diaminotoluene → HCID 178494311, 화합물

HRID 12279

반응식

HRID 12279 반응식
[Cl:1][C:2]1[N:7]=[N:6][C:5]([O:8][CH3:9])=[C:4]([CH:10]=O)[CH:3]=1.[NH2:12][C:13]1[C:18]([NH2:19])=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:20]>CN(C=O)C>[Cl:1][C:2]1[N:7]=[N:6][C:5]([O:8][CH3:9])=[C:4]([C:10]2[NH:12][C:13]3[C:14]([CH3:20])=[CH:15][CH:16]=[CH:17][C:18]=3[N:19]=2)[CH:3]=1

참가 물질

4

반응물 2

HCID 175932,3-DiaminotolueneHCID 840488116-Chloro-3-methoxypyridazine-4-carbaldehyde

생성물 1

HCID 178494311HCID 178494311, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
120 °C

실험 절차

6-Chloro-3-methoxypyridazine-4-carbaldehyde is dissolved in DMF, und 2,3-diaminotoluene is added. The reaction solution is heated at 120° C. in a microwave for 30 minutes. The crude product is purified on silica gel (eluent ethyl acetate in heptane). MS (ES+) m/z 275 (M+H).

후처리

  1. customThe crude product is purified on silica gel (eluent ethyl acetate in heptane)

출처 및 근거

ORD 기록
ord-e986e39eba024f0d9b164fdcba6d54bc
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07727989B2

연결된 노트

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