Hydrochloric Acid → Benzenesulfonyl azide

HRID 1248968

반응식

HRID 1248968 반응식
[C:1]1([S:7]([NH:10][NH2:11])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.C(O)(=O)CCCCCCCCCCCCCCCCC.[NH2:33]CCS(O)(=O)=O.N([O-])=O.[Na+].N([O-])=O>O>[C:1]1([S:7]([N:10]=[N+:11]=[N-:33])(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

8

반응물 6

HCID 313Hydrochloric AcidHCID 946NitriteHCID 1123TaurineHCID 5281Stearic AcidHCID 65723Benzenesulfonyl hydrazideHCID 23668193Sodium Nitrite2회

생성물 1

HCID 555606Benzenesulfonyl azide

시약·촉매·용매 1

HCID 962Water용매

실험 절차

25 g of benzenesulphonohydrazide, 200 ml of water, 20 ml of 10N hydrochloric acid and 1.25 g of a product of condensing stearic acid with taurine are stirred for 30 minutes. 60 g of ice are added, and 34 ml of an aqueous sodium nitrite solution containing 30 g of sodium nitrite in 100 ml of solution are then added dropwise in the course of about 30 minutes. The batch is stirred for 30 minutes, an excess of nitrite being maintained. The nitrite excess is then destroyed with a small amount of sulphamic acid, and excess acid is neutralised with about 5 ml of 10N sodium hydroxide solution (pH 4-7). An emulsion of benzenesulphonyl azide is obtained.

후처리

  1. additionare then added dropwise in the course of about 30 minutes
  2. stirringThe batch is stirred for 30 minutes
  3. customThe nitrite excess is then destroyed with a small amount of sulphamic acid, and excess acid

출처 및 근거

ORD 기록
ord-b45bee630a1c46ea9ae5b840ee2739d9
출처 데이터셋
uspto-grants-1986_12
특허 번호
US04628082

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